A serum factor after intestinal resection stimulates epidermal growth factor receptor signaling and proliferation in intestinal epithelial cells

Background. In vivo, intestinal adaptation after massive small bowel resection (SBR) requires a functional epidermal growth factor (EGF) receptor (EGFR). In vitro studies have shown that serum from mice after SBR induces rat intestinal epithelial cells to proliferate. This study tested the hypothesi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Surgery 2002-08, Vol.132 (2), p.377-383
Hauptverfasser:	Juno, Russell J., Williams, Jodi L., Knott, Andrew W., Erwin, Christopher R., O'Brien, David P., Warner, Brad W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological - physiology Animals Biological and medical sciences Blood Proteins - pharmacology Cell Division - drug effects Cell Division - physiology Enzyme Inhibitors - pharmacology Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Intestine, Small - surgery Male Medical sciences Phosphatidylinositol 3-Kinases - metabolism Quinazolines - pharmacology Rats Rats, Sprague-Dawley Receptor, Epidermal Growth Factor - metabolism Signal Transduction - physiology Stomach, duodenum, intestine, rectum, anus Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!