Effects of raloxifene on bone density, biomarkers, and histomorphometric and biomechanical measures in ovariectomized cynomolgus monkeys

OBJECTIVEThe purpose of this study was to determine the effect of raloxifene on bone density, strength, metabolism, and histomorphometric characteristics in ovariectomized cynomolgus monkeys. DESIGNA prospective, longitudinal study was designed to examine the effects of conjugated equine estrogens (...

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Veröffentlicht in:	Menopause (New York, N.Y.) N.Y.), 2002-09, Vol.9 (5), p.320-328
Hauptverfasser:	Lees, Cynthia J., Register, Thomas C., Turner, Charles H., Wang, Tongyu, Stancill, Melanie, Jerome, Christopher P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Animals Biomarkers - blood Biomechanical Phenomena Bone Density - drug effects Bone Diseases, Metabolic - prevention & control Bone Remodeling - drug effects Female Femur - anatomy & histology Femur - drug effects Ilium - anatomy & histology Ilium - drug effects Macaca fascicularis - blood Macaca fascicularis - metabolism Ovariectomy Raloxifene Hydrochloride - pharmacology Selective Estrogen Receptor Modulators - pharmacology Time Factors
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