Mycosis fungoides causing severe lower eyelid ulceration
Mycosis fungoides is a form of cutaneous malignant T‐cell lymphoma initially confined to the skin. A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening a...
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Veröffentlicht in: | Clinical & experimental ophthalmology 2002-10, Vol.30 (5), p.369-371 |
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description | Mycosis fungoides is a form of cutaneous malignant T‐cell lymphoma initially confined to the skin. A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening and placoid tumours. A case of a 72‐year‐old man presenting with progressive, full thickness, lower eyelid ulceration is presented. The patient had a long history of placoid skin lesions, previously diagnosed as discoid lupus. Repeat biopsies of these lesions including the eyelid eventually revealed mycosis fungoides. The ulceration progressed to destroy most of the lower lid before the correct diagnosis was made. This type of eyelid involvement has not previously been reported in mycosis fungoides. This case also highlights the diagnostic difficulties encountered in the early phases of mycosis fungoides. If suspected, multiple biopsies are essential to establish the diagnosis. |
doi_str_mv | 10.1046/j.1442-9071.2002.00559.x |
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A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening and placoid tumours. A case of a 72‐year‐old man presenting with progressive, full thickness, lower eyelid ulceration is presented. The patient had a long history of placoid skin lesions, previously diagnosed as discoid lupus. Repeat biopsies of these lesions including the eyelid eventually revealed mycosis fungoides. The ulceration progressed to destroy most of the lower lid before the correct diagnosis was made. This type of eyelid involvement has not previously been reported in mycosis fungoides. This case also highlights the diagnostic difficulties encountered in the early phases of mycosis fungoides. If suspected, multiple biopsies are essential to establish the diagnosis.</description><identifier>ISSN: 1442-6404</identifier><identifier>EISSN: 1442-9071</identifier><identifier>DOI: 10.1046/j.1442-9071.2002.00559.x</identifier><identifier>PMID: 12213165</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Pty</publisher><subject>Aged ; eyelid ; Eyelid Diseases - etiology ; Eyelid Diseases - pathology ; Humans ; lymphoma ; Male ; mycosis fungoides ; Mycosis Fungoides - complications ; Mycosis Fungoides - diagnosis ; Skin Neoplasms - complications ; Skin Neoplasms - diagnosis ; Ulcer - etiology ; Ulcer - pathology ; ulceration</subject><ispartof>Clinical & experimental ophthalmology, 2002-10, Vol.30 (5), p.369-371</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4029-72a1e2b32c9ebffb480a8c8c9337290e80e67b86b12973127a8ba0aea082af503</citedby><cites>FETCH-LOGICAL-c4029-72a1e2b32c9ebffb480a8c8c9337290e80e67b86b12973127a8ba0aea082af503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1442-9071.2002.00559.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1442-9071.2002.00559.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12213165$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Game, Justin A</creatorcontrib><creatorcontrib>Davies, Rodger</creatorcontrib><title>Mycosis fungoides causing severe lower eyelid ulceration</title><title>Clinical & experimental ophthalmology</title><addtitle>Clin Exp Ophthalmol</addtitle><description>Mycosis fungoides is a form of cutaneous malignant T‐cell lymphoma initially confined to the skin. A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening and placoid tumours. A case of a 72‐year‐old man presenting with progressive, full thickness, lower eyelid ulceration is presented. The patient had a long history of placoid skin lesions, previously diagnosed as discoid lupus. Repeat biopsies of these lesions including the eyelid eventually revealed mycosis fungoides. The ulceration progressed to destroy most of the lower lid before the correct diagnosis was made. This type of eyelid involvement has not previously been reported in mycosis fungoides. This case also highlights the diagnostic difficulties encountered in the early phases of mycosis fungoides. If suspected, multiple biopsies are essential to establish the diagnosis.</description><subject>Aged</subject><subject>eyelid</subject><subject>Eyelid Diseases - etiology</subject><subject>Eyelid Diseases - pathology</subject><subject>Humans</subject><subject>lymphoma</subject><subject>Male</subject><subject>mycosis fungoides</subject><subject>Mycosis Fungoides - complications</subject><subject>Mycosis Fungoides - diagnosis</subject><subject>Skin Neoplasms - complications</subject><subject>Skin Neoplasms - diagnosis</subject><subject>Ulcer - etiology</subject><subject>Ulcer - pathology</subject><subject>ulceration</subject><issn>1442-6404</issn><issn>1442-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1LwzAUQIMoOqd_QfrkW-tN0jYJ-CJjH8J0CIqPIc1uJbNbZ7Lq9u9t3dBXn3Ih59wLh5CIQkIhzW8WCU1TFisQNGEALAHIMpVsj0jv9-P4MOcppGfkPIQFtBTj-Sk5o4xRTvOsR-TDztbBhahsVm-1m2OIrGmCW71FAT_RY1TVX-gj3GHl5lFTWfRm4-rVBTkpTRXw8vD2ycto-DyYxNPZ-H5wN41tCkzFghmKrODMKizKskglGGmlVZwLpgAlYC4KmReUKcEpE0YWBgwakMyUGfA-ud7vXfv6o8Gw0UsXLFaVWWHdBC0Y5EKJDpR70Po6BI-lXnu3NH6nKeiuml7oLoju4uiumv6ppretenW40RRLnP-Jh0wtcLsHvlyFu38v1oPhrB1aPd7rLmxw-6sb_65zwUWmXx_HejThT2qSCT3m35D1iWQ</recordid><startdate>200210</startdate><enddate>200210</enddate><creator>Game, Justin A</creator><creator>Davies, Rodger</creator><general>Blackwell Science Pty</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200210</creationdate><title>Mycosis fungoides causing severe lower eyelid ulceration</title><author>Game, Justin A ; Davies, Rodger</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4029-72a1e2b32c9ebffb480a8c8c9337290e80e67b86b12973127a8ba0aea082af503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Aged</topic><topic>eyelid</topic><topic>Eyelid Diseases - etiology</topic><topic>Eyelid Diseases - pathology</topic><topic>Humans</topic><topic>lymphoma</topic><topic>Male</topic><topic>mycosis fungoides</topic><topic>Mycosis Fungoides - complications</topic><topic>Mycosis Fungoides - diagnosis</topic><topic>Skin Neoplasms - complications</topic><topic>Skin Neoplasms - diagnosis</topic><topic>Ulcer - etiology</topic><topic>Ulcer - pathology</topic><topic>ulceration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Game, Justin A</creatorcontrib><creatorcontrib>Davies, Rodger</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical & experimental ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Game, Justin A</au><au>Davies, Rodger</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mycosis fungoides causing severe lower eyelid ulceration</atitle><jtitle>Clinical & experimental ophthalmology</jtitle><addtitle>Clin Exp Ophthalmol</addtitle><date>2002-10</date><risdate>2002</risdate><volume>30</volume><issue>5</issue><spage>369</spage><epage>371</epage><pages>369-371</pages><issn>1442-6404</issn><eissn>1442-9071</eissn><abstract>Mycosis fungoides is a form of cutaneous malignant T‐cell lymphoma initially confined to the skin. A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening and placoid tumours. A case of a 72‐year‐old man presenting with progressive, full thickness, lower eyelid ulceration is presented. The patient had a long history of placoid skin lesions, previously diagnosed as discoid lupus. Repeat biopsies of these lesions including the eyelid eventually revealed mycosis fungoides. The ulceration progressed to destroy most of the lower lid before the correct diagnosis was made. This type of eyelid involvement has not previously been reported in mycosis fungoides. This case also highlights the diagnostic difficulties encountered in the early phases of mycosis fungoides. If suspected, multiple biopsies are essential to establish the diagnosis.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Pty</pub><pmid>12213165</pmid><doi>10.1046/j.1442-9071.2002.00559.x</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Aged eyelid Eyelid Diseases - etiology Eyelid Diseases - pathology Humans lymphoma Male mycosis fungoides Mycosis Fungoides - complications Mycosis Fungoides - diagnosis Skin Neoplasms - complications Skin Neoplasms - diagnosis Ulcer - etiology Ulcer - pathology ulceration |
title | Mycosis fungoides causing severe lower eyelid ulceration |
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