Variations in the Myocilin Gene in Patients With Open-Angle Glaucoma

OBJECTIVE To determine the prevalence and associated phenotype of myocilin (MYOC) coding sequence variations and a specific promoter polymorphism(MYOC.mt1) in patients with glaucoma and glaucoma suspects. METHODS A consecutive, unselected series of 779 patients (652 with open-angle glaucoma and 127...

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Veröffentlicht in:	Archives of ophthalmology (1960) 2002-09, Vol.120 (9), p.1189-1197
Hauptverfasser:	Alward, Wallace L. M, Kwon, Young H, Khanna, Cheryl L, Johnson, A. Tim, Hayreh, Sohan S, Zimmerman, M. Bridget, Narkiewicz, Joanna, Andorf, Jeaneen L, Moore, Paula A, Fingert, John H, Sheffield, Val C, Stone, Edwin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Cytoskeletal Proteins Eye Proteins - genetics Female Genetic Variation - genetics Glaucoma Glaucoma, Open-Angle - genetics Glycoproteins - genetics Humans Male Middle Aged Phenotype Polymorphism, Genetic Prevalence Sequence Analysis, DNA
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