Characterization of the complexes of furosemide with 2-hydroxypropyl-β-cyclodextrin and sulfobutyl ether-7-β-cyclodextrin

The purpose of this study was to prepare and characterize complexes of furosemide with 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD) and sulfobutyl ether-7-β-cyclodextrin (SBE-7-β-CD). Solid complexes of furosemide with 2-HP-β-CD and SBE-7-β-CD were prepared by using both a freeze–drying and kneading m...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2002-09, Vol.16 (4), p.247-253
Hauptverfasser:	Spamer, Elisma, Müller, Douw G, Wessels, Philippus L, Venter, Johannes P
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Hydroxypropyl-beta-cyclodextrin 2-Hydroxypropyl-β-cyclodextrin beta-Cyclodextrins Calorimetry, Differential Scanning Complexation Cyclodextrins - chemistry Drug Compounding Freeze Drying Furosemide Furosemide - chemistry Magnetic Resonance Spectroscopy Models, Molecular Molecular Structure Solubility Sulfobutyl ether-7-β-cyclodextrin X-Ray Diffraction
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