Effect of Locally Delivered Minocycline Microspheres on Markers of Bone Resorption

Background: Gingival crevicular fluid (GCF) biomarkers associated with bone resorption may be useful to determine periodontal disease status and response to therapy. The pyridinoline cross‐linked carboxy‐terminal telopeptide of type I collagen (ICTP), a bone‐specific degradation product, and interle...

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Veröffentlicht in:	Journal of periodontology (1970) 2002-08, Vol.73 (8), p.835-842
Hauptverfasser:	Oringer, R.J., Al‐Shammari, K.F., Aldredge, W.A., Iacono, V.J., Eber, R.M., Wang, H.L., Berwald, B., Nejat, R., Giannobile, W.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adult Aged Analysis of Variance Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Biomarkers - analysis Bone resorption Bone Resorption - drug therapy Bone Resorption - therapy Chronic Disease clinical trials collagen Collagen - analysis Collagen - drug effects Collagen Type I Dental Scaling Dentistry drug delivery systems Female Follow-Up Studies Gingival Crevicular Fluid - chemistry Gingival Hemorrhage - drug therapy Gingival Hemorrhage - therapy Humans Interleukin-1 - analysis interleukin‐1 Male Matched-Pair Analysis Microspheres Middle Aged Minocycline - administration & dosage Minocycline - therapeutic use Peptides - analysis Peptides - drug effects Periodontal Attachment Loss - drug therapy Periodontal Attachment Loss - therapy periodontal diseases/therapy Periodontal Pocket - drug therapy Periodontal Pocket - therapy Periodontitis - drug therapy Periodontitis - therapy pyridinoline cross‐links Root Planing Single-Blind Method Statistics as Topic
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