Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: Successful management with transfusions
The investigation and treatment of a pregnant thalassemic woman who developed severe paraplegia is presented. Magnetic resonance imaging showed a paravertebral mass infiltrating the epidural space, resulting from extramedullary hematopoiesis (marrow heterotopia). The patient was treated successfully...
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| Veröffentlicht in: | Surgical neurology 1991-09, Vol.36 (3), p.210-215 |
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| container_title | Surgical neurology |
| container_volume | 36 |
| creator | Singounas, E.G. Sakas, D.E. Hadley, D.M. Chalevelakis, G. Sfakianos, G. Raptis, S. Karvounis, P.C. |
| description | The investigation and treatment of a pregnant thalassemic woman who developed severe paraplegia is presented. Magnetic resonance imaging showed a paravertebral mass infiltrating the epidural space, resulting from extramedullary hematopoiesis (marrow heterotopia). The patient was treated successfully with repeated blood transfusions and made a complete recovery. The literature (36 cases) is reviewed and the magnetic resonance imaging features of spinal extramedullary hematopoiesis are presented. The efficacy of transfusions in the management of spinal cord compression due to marrow heterotopia in thalassemic patients is discussed. |
| doi_str_mv | 10.1016/0090-3019(91)90115-P |
| format | Article |
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Magnetic resonance imaging showed a paravertebral mass infiltrating the epidural space, resulting from extramedullary hematopoiesis (marrow heterotopia). The patient was treated successfully with repeated blood transfusions and made a complete recovery. The literature (36 cases) is reviewed and the magnetic resonance imaging features of spinal extramedullary hematopoiesis are presented. The efficacy of transfusions in the management of spinal cord compression due to marrow heterotopia in thalassemic patients is discussed.</description><identifier>ISSN: 0090-3019</identifier><identifier>EISSN: 1879-3339</identifier><identifier>DOI: 10.1016/0090-3019(91)90115-P</identifier><identifier>PMID: 1876971</identifier><identifier>CODEN: SGNRAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Anemias. Hemoglobinopathies ; Biological and medical sciences ; Blood Transfusion ; Diseases of red blood cells ; Extramedullary hematopoiesis ; Female ; Hematologic and hematopoietic diseases ; Hematopoiesis, Extramedullary - physiology ; Humans ; Magnetic resonance imaging ; Medical sciences ; Paraplegia - etiology ; Pregnancy ; Pregnancy Complications, Hematologic - physiopathology ; Pregnancy Complications, Hematologic - therapy ; Spinal cord compression ; Spinal Cord Compression - complications ; Spinal Cord Compression - etiology ; Thalassemia ; Thalassemia - complications ; Thalassemia - physiopathology ; Thalassemia - therapy</subject><ispartof>Surgical neurology, 1991-09, Vol.36 (3), p.210-215</ispartof><rights>1991</rights><rights>1992 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-262ef051068bc54a15fa443c9417598cd0c5a9e81e0a97df6fccef44ac6a112b3</citedby><cites>FETCH-LOGICAL-c386t-262ef051068bc54a15fa443c9417598cd0c5a9e81e0a97df6fccef44ac6a112b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5596862$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1876971$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singounas, E.G.</creatorcontrib><creatorcontrib>Sakas, D.E.</creatorcontrib><creatorcontrib>Hadley, D.M.</creatorcontrib><creatorcontrib>Chalevelakis, G.</creatorcontrib><creatorcontrib>Sfakianos, G.</creatorcontrib><creatorcontrib>Raptis, S.</creatorcontrib><creatorcontrib>Karvounis, P.C.</creatorcontrib><title>Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: Successful management with transfusions</title><title>Surgical neurology</title><addtitle>Surg Neurol</addtitle><description>The investigation and treatment of a pregnant thalassemic woman who developed severe paraplegia is presented. Magnetic resonance imaging showed a paravertebral mass infiltrating the epidural space, resulting from extramedullary hematopoiesis (marrow heterotopia). The patient was treated successfully with repeated blood transfusions and made a complete recovery. The literature (36 cases) is reviewed and the magnetic resonance imaging features of spinal extramedullary hematopoiesis are presented. The efficacy of transfusions in the management of spinal cord compression due to marrow heterotopia in thalassemic patients is discussed.</description><subject>Adult</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion</subject><subject>Diseases of red blood cells</subject><subject>Extramedullary hematopoiesis</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hematopoiesis, Extramedullary - physiology</subject><subject>Humans</subject><subject>Magnetic resonance imaging</subject><subject>Medical sciences</subject><subject>Paraplegia - etiology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Hematologic - physiopathology</subject><subject>Pregnancy Complications, Hematologic - therapy</subject><subject>Spinal cord compression</subject><subject>Spinal Cord Compression - complications</subject><subject>Spinal Cord Compression - etiology</subject><subject>Thalassemia</subject><subject>Thalassemia - complications</subject><subject>Thalassemia - physiopathology</subject><subject>Thalassemia - therapy</subject><issn>0090-3019</issn><issn>1879-3339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAQhi0EKtvCPwDJB4TgkGInsRNzQEJVKZUqsRJwtmad8a5RvvA4Xfj3eNlVuXHy4X3e8czD2AspLqWQ-p0QRhSVkOaNkW-NkFIV60dsJdvGFFVVmcds9YA8ZedEP4QQlVHmjJ1lSJtGrth-DRHmHrcBeBg58DnidoQx8bSDHohwCI7vpwFG3i3I08TxV4owYLf0PcTffIcDpGmeAlKg9_zr4hwS-aXnuQNbHDAP24e047k25oDCNNIz9sRDT_j89F6w75-uv119Lu6-3NxefbwrXNXqVJS6RC-UFLrdOFWDVB7qunKmlo0yreuEU2CwlSjANJ3XPv_u6xqcBinLTXXBXh_nznH6uSAlOwRymFcfcVrINqVQupUig_URdHEiiujtHMOQD7RS2INve5BpDzKtkfavb7vOtZen-csmO_lXOgrO-atTDuSg91mBC_SAKWV0q8uMfThimF3cB4yWXMDRYRciumS7Kfx_jz-hcJ81</recordid><startdate>19910901</startdate><enddate>19910901</enddate><creator>Singounas, E.G.</creator><creator>Sakas, D.E.</creator><creator>Hadley, D.M.</creator><creator>Chalevelakis, G.</creator><creator>Sfakianos, G.</creator><creator>Raptis, S.</creator><creator>Karvounis, P.C.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19910901</creationdate><title>Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: Successful management with transfusions</title><author>Singounas, E.G. ; Sakas, D.E. ; Hadley, D.M. ; Chalevelakis, G. ; Sfakianos, G. ; Raptis, S. ; Karvounis, P.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-262ef051068bc54a15fa443c9417598cd0c5a9e81e0a97df6fccef44ac6a112b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adult</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion</topic><topic>Diseases of red blood cells</topic><topic>Extramedullary hematopoiesis</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hematopoiesis, Extramedullary - physiology</topic><topic>Humans</topic><topic>Magnetic resonance imaging</topic><topic>Medical sciences</topic><topic>Paraplegia - etiology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Hematologic - physiopathology</topic><topic>Pregnancy Complications, Hematologic - therapy</topic><topic>Spinal cord compression</topic><topic>Spinal Cord Compression - complications</topic><topic>Spinal Cord Compression - etiology</topic><topic>Thalassemia</topic><topic>Thalassemia - complications</topic><topic>Thalassemia - physiopathology</topic><topic>Thalassemia - therapy</topic><toplevel>online_resources</toplevel><creatorcontrib>Singounas, E.G.</creatorcontrib><creatorcontrib>Sakas, D.E.</creatorcontrib><creatorcontrib>Hadley, D.M.</creatorcontrib><creatorcontrib>Chalevelakis, G.</creatorcontrib><creatorcontrib>Sfakianos, G.</creatorcontrib><creatorcontrib>Raptis, S.</creatorcontrib><creatorcontrib>Karvounis, P.C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singounas, E.G.</au><au>Sakas, D.E.</au><au>Hadley, D.M.</au><au>Chalevelakis, G.</au><au>Sfakianos, G.</au><au>Raptis, S.</au><au>Karvounis, P.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: Successful management with transfusions</atitle><jtitle>Surgical neurology</jtitle><addtitle>Surg Neurol</addtitle><date>1991-09-01</date><risdate>1991</risdate><volume>36</volume><issue>3</issue><spage>210</spage><epage>215</epage><pages>210-215</pages><issn>0090-3019</issn><eissn>1879-3339</eissn><coden>SGNRAI</coden><abstract>The investigation and treatment of a pregnant thalassemic woman who developed severe paraplegia is presented. Magnetic resonance imaging showed a paravertebral mass infiltrating the epidural space, resulting from extramedullary hematopoiesis (marrow heterotopia). The patient was treated successfully with repeated blood transfusions and made a complete recovery. The literature (36 cases) is reviewed and the magnetic resonance imaging features of spinal extramedullary hematopoiesis are presented. The efficacy of transfusions in the management of spinal cord compression due to marrow heterotopia in thalassemic patients is discussed.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>1876971</pmid><doi>10.1016/0090-3019(91)90115-P</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Surgical neurology, 1991-09, Vol.36 (3), p.210-215 |
| issn | 0090-3019 1879-3339 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Anemias. Hemoglobinopathies Biological and medical sciences Blood Transfusion Diseases of red blood cells Extramedullary hematopoiesis Female Hematologic and hematopoietic diseases Hematopoiesis, Extramedullary - physiology Humans Magnetic resonance imaging Medical sciences Paraplegia - etiology Pregnancy Pregnancy Complications, Hematologic - physiopathology Pregnancy Complications, Hematologic - therapy Spinal cord compression Spinal Cord Compression - complications Spinal Cord Compression - etiology Thalassemia Thalassemia - complications Thalassemia - physiopathology Thalassemia - therapy |
| title | Paraplegia in a pregnant thalassemic woman due to extramedullary hematopoiesis: Successful management with transfusions |
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