Universal or selective screening of the neonatal hip using ultrasound? A prospective, randomised trial of 15 529 newborn infants
The aim of this study was to evaluate whether universal (all neonates) or selective (neonates belonging to the risk groups) ultrasound screening of the hips should be recommended at birth. We carried out a prospective, randomised trial between 1988 and 1992, including all newborn infants at our hosp...
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Veröffentlicht in: | Journal of bone and joint surgery. British volume 2002-08, Vol.84 (6), p.886-890 |
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creator | HOLEN, K. J TEGNANDER, A BREDLAND, T JOHANSEN, O. J SAETHER, O. D EIK-NES, S. H TERJESEN, T |
description | The aim of this study was to evaluate whether universal (all neonates) or selective (neonates belonging to the risk groups) ultrasound screening of the hips should be recommended at birth. We carried out a prospective, randomised trial between 1988 and 1992, including all newborn infants at our hospital. A total of 15 529 infants was randomised to either clinical screening and ultrasound examination of all hips or clinical screening of all hips and ultrasound examination only of those at risk. The effect of the screening was assessed by the rate of late detection of congenital or developmental hip dysplasia in the two groups. During follow-up of between six and 11 years, only one late-detected hip dysplasia was seen in the universal group, compared with five in the subjective group, representing a rate of 0.13 and 0.65 per 1,000, respectively. The difference in late detection between the two groups was not statistically significant (p = 0.22). When clinical screening is of high quality, as in our study, the effect of an additional ultrasound examination, measured as late-presenting hip dysplasia, is marginal. Under such circumstances, we consider that universal ultrasound screening is not necessary, but recommend selective ultrasound screening for neonates with abnormal or suspicious clinical findings and those with risk factors for hip dysplasia. |
doi_str_mv | 10.1302/0301-620X.84B6.0840886 |
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A prospective, randomised trial of 15 529 newborn infants</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>HOLEN, K. J ; TEGNANDER, A ; BREDLAND, T ; JOHANSEN, O. J ; SAETHER, O. D ; EIK-NES, S. H ; TERJESEN, T</creator><creatorcontrib>HOLEN, K. J ; TEGNANDER, A ; BREDLAND, T ; JOHANSEN, O. J ; SAETHER, O. D ; EIK-NES, S. H ; TERJESEN, T</creatorcontrib><description>The aim of this study was to evaluate whether universal (all neonates) or selective (neonates belonging to the risk groups) ultrasound screening of the hips should be recommended at birth. We carried out a prospective, randomised trial between 1988 and 1992, including all newborn infants at our hospital. A total of 15 529 infants was randomised to either clinical screening and ultrasound examination of all hips or clinical screening of all hips and ultrasound examination only of those at risk. The effect of the screening was assessed by the rate of late detection of congenital or developmental hip dysplasia in the two groups. During follow-up of between six and 11 years, only one late-detected hip dysplasia was seen in the universal group, compared with five in the subjective group, representing a rate of 0.13 and 0.65 per 1,000, respectively. The difference in late detection between the two groups was not statistically significant (p = 0.22). When clinical screening is of high quality, as in our study, the effect of an additional ultrasound examination, measured as late-presenting hip dysplasia, is marginal. Under such circumstances, we consider that universal ultrasound screening is not necessary, but recommend selective ultrasound screening for neonates with abnormal or suspicious clinical findings and those with risk factors for hip dysplasia.</description><edition>British volume</edition><identifier>ISSN: 0301-620X</identifier><identifier>ISSN: 2049-4394</identifier><identifier>EISSN: 2044-5377</identifier><identifier>EISSN: 2049-4408</identifier><identifier>DOI: 10.1302/0301-620X.84B6.0840886</identifier><identifier>PMID: 12211684</identifier><identifier>CODEN: JBSUAK</identifier><language>eng</language><publisher>London: British Editorial Society of Bone and Joint Surgery</publisher><subject>Algorithms ; Biological and medical sciences ; Female ; Hip - abnormalities ; Hip - diagnostic imaging ; Hip Dislocation, Congenital - diagnostic imaging ; Humans ; Infant, Newborn ; Investigative techniques, diagnostic techniques (general aspects) ; Joint Instability - diagnostic imaging ; Joints ; Male ; Medical sciences ; Neonatal Screening - methods ; Prospective Studies ; Risk Factors ; Ultrasonic investigative techniques ; Ultrasonography</subject><ispartof>Journal of bone and joint surgery. British volume, 2002-08, Vol.84 (6), p.886-890</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright British Editorial Society of Bone & Joint Surgery Aug 2002</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13842657$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12211684$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HOLEN, K. J</creatorcontrib><creatorcontrib>TEGNANDER, A</creatorcontrib><creatorcontrib>BREDLAND, T</creatorcontrib><creatorcontrib>JOHANSEN, O. J</creatorcontrib><creatorcontrib>SAETHER, O. D</creatorcontrib><creatorcontrib>EIK-NES, S. H</creatorcontrib><creatorcontrib>TERJESEN, T</creatorcontrib><title>Universal or selective screening of the neonatal hip using ultrasound? A prospective, randomised trial of 15 529 newborn infants</title><title>Journal of bone and joint surgery. British volume</title><addtitle>J Bone Joint Surg Br</addtitle><description>The aim of this study was to evaluate whether universal (all neonates) or selective (neonates belonging to the risk groups) ultrasound screening of the hips should be recommended at birth. We carried out a prospective, randomised trial between 1988 and 1992, including all newborn infants at our hospital. A total of 15 529 infants was randomised to either clinical screening and ultrasound examination of all hips or clinical screening of all hips and ultrasound examination only of those at risk. The effect of the screening was assessed by the rate of late detection of congenital or developmental hip dysplasia in the two groups. During follow-up of between six and 11 years, only one late-detected hip dysplasia was seen in the universal group, compared with five in the subjective group, representing a rate of 0.13 and 0.65 per 1,000, respectively. The difference in late detection between the two groups was not statistically significant (p = 0.22). When clinical screening is of high quality, as in our study, the effect of an additional ultrasound examination, measured as late-presenting hip dysplasia, is marginal. Under such circumstances, we consider that universal ultrasound screening is not necessary, but recommend selective ultrasound screening for neonates with abnormal or suspicious clinical findings and those with risk factors for hip dysplasia.</description><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Hip - abnormalities</subject><subject>Hip - diagnostic imaging</subject><subject>Hip Dislocation, Congenital - diagnostic imaging</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Joint Instability - diagnostic imaging</subject><subject>Joints</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neonatal Screening - methods</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Ultrasonic investigative techniques</subject><subject>Ultrasonography</subject><issn>0301-620X</issn><issn>2049-4394</issn><issn>2044-5377</issn><issn>2049-4408</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUtLAzEUhYMoWh9_oQRBV7bmPelKqvgCwY0Fd-E2k-jINFOTGcWdP90MHRRcJSTfOZx7D0JjSqaUE3ZOOKETxcjzVItLNSVaEK3VFhoxIsRE8qLYRqNfaA_tp_RGCBFS8l20RxmjVGkxQt-LUH24mKDGTcTJ1c62-QEnG50LVXjBjcftq8PBNQHajL1Wa9yl_qer2wip6UJ5ged4HZu03qjPcIRQNqsquRK3serNPaYSSzbLRp_LJgZcBQ-hTYdox0Od3NFwHqDFzfXT1d3k4fH2_mr-MLFU6jyRV2ChnC0L4gEcAEhgVsvCUe0FME-JZV6V1oItQRYahOalBrnMV-IlP0CnG9-c871zqTU5nnV1DXmyLpmCESk14xk8_ge-NV0MOZthbKb0TFKdIbWBbJ46RefNOlYriF-GEtMXZPrdm373pi_IDAVl4Xhw75YrV_7JhkYycDIAkCzUPm_SVumP41owJQv-Ay_CmrU</recordid><startdate>200208</startdate><enddate>200208</enddate><creator>HOLEN, K. J</creator><creator>TEGNANDER, A</creator><creator>BREDLAND, T</creator><creator>JOHANSEN, O. J</creator><creator>SAETHER, O. D</creator><creator>EIK-NES, S. H</creator><creator>TERJESEN, T</creator><general>British Editorial Society of Bone and Joint Surgery</general><general>British Editorial Society of Bone & Joint Surgery</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>200208</creationdate><title>Universal or selective screening of the neonatal hip using ultrasound? A prospective, randomised trial of 15 529 newborn infants</title><author>HOLEN, K. J ; TEGNANDER, A ; BREDLAND, T ; JOHANSEN, O. J ; SAETHER, O. D ; EIK-NES, S. H ; TERJESEN, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1584-5f6acad9b70faaeaaa5a2c857e18f4a2f10c2f6dccacda578a483d8a5b78a0f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Hip - abnormalities</topic><topic>Hip - diagnostic imaging</topic><topic>Hip Dislocation, Congenital - diagnostic imaging</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Joint Instability - diagnostic imaging</topic><topic>Joints</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neonatal Screening - methods</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Ultrasonic investigative techniques</topic><topic>Ultrasonography</topic><toplevel>online_resources</toplevel><creatorcontrib>HOLEN, K. J</creatorcontrib><creatorcontrib>TEGNANDER, A</creatorcontrib><creatorcontrib>BREDLAND, T</creatorcontrib><creatorcontrib>JOHANSEN, O. J</creatorcontrib><creatorcontrib>SAETHER, O. D</creatorcontrib><creatorcontrib>EIK-NES, S. H</creatorcontrib><creatorcontrib>TERJESEN, T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of bone and joint surgery. British volume</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HOLEN, K. J</au><au>TEGNANDER, A</au><au>BREDLAND, T</au><au>JOHANSEN, O. J</au><au>SAETHER, O. D</au><au>EIK-NES, S. H</au><au>TERJESEN, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Universal or selective screening of the neonatal hip using ultrasound? A prospective, randomised trial of 15 529 newborn infants</atitle><jtitle>Journal of bone and joint surgery. British volume</jtitle><addtitle>J Bone Joint Surg Br</addtitle><date>2002-08</date><risdate>2002</risdate><volume>84</volume><issue>6</issue><spage>886</spage><epage>890</epage><pages>886-890</pages><issn>0301-620X</issn><issn>2049-4394</issn><eissn>2044-5377</eissn><eissn>2049-4408</eissn><coden>JBSUAK</coden><abstract>The aim of this study was to evaluate whether universal (all neonates) or selective (neonates belonging to the risk groups) ultrasound screening of the hips should be recommended at birth. We carried out a prospective, randomised trial between 1988 and 1992, including all newborn infants at our hospital. A total of 15 529 infants was randomised to either clinical screening and ultrasound examination of all hips or clinical screening of all hips and ultrasound examination only of those at risk. The effect of the screening was assessed by the rate of late detection of congenital or developmental hip dysplasia in the two groups. During follow-up of between six and 11 years, only one late-detected hip dysplasia was seen in the universal group, compared with five in the subjective group, representing a rate of 0.13 and 0.65 per 1,000, respectively. The difference in late detection between the two groups was not statistically significant (p = 0.22). When clinical screening is of high quality, as in our study, the effect of an additional ultrasound examination, measured as late-presenting hip dysplasia, is marginal. Under such circumstances, we consider that universal ultrasound screening is not necessary, but recommend selective ultrasound screening for neonates with abnormal or suspicious clinical findings and those with risk factors for hip dysplasia.</abstract><cop>London</cop><pub>British Editorial Society of Bone and Joint Surgery</pub><pmid>12211684</pmid><doi>10.1302/0301-620X.84B6.0840886</doi><tpages>5</tpages><edition>British volume</edition></addata></record> |
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subjects | Algorithms Biological and medical sciences Female Hip - abnormalities Hip - diagnostic imaging Hip Dislocation, Congenital - diagnostic imaging Humans Infant, Newborn Investigative techniques, diagnostic techniques (general aspects) Joint Instability - diagnostic imaging Joints Male Medical sciences Neonatal Screening - methods Prospective Studies Risk Factors Ultrasonic investigative techniques Ultrasonography |
title | Universal or selective screening of the neonatal hip using ultrasound? A prospective, randomised trial of 15 529 newborn infants |
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