Image cytometric bcl‐2:bax and bcl‐2:bcl‐x ratios in invasive breast carcinoma: Correlation with prognosis

Background: The bcl‐2 family of proteins are important regulators of apoptosis. Some of the members, such as bcl‐2 and bcl‐xL, inhibit cell death, whereas others, such as bax and bcl‐xS, promote cell death. We evaluated the ratios of bcl‐2:bax and bcl‐2:bcl‐x expression by image cytometry in invasiv...

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