A Novel Biosynthetic Pathway Providing Precursors for Fatty Acid Biosynthesis and Secondary Metabolite Formation in Myxobacteria

Short chain carboxylic acids are well known as the precursors of fatty acid and polyketide biosynthesis. Iso-fatty acids, which are important for the control of membrane fluidity, are formed from branched chain starter units (isovaleryl-CoA and isobutyryl-CoA), which in turn are derived from the deg...

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Veröffentlicht in:	The Journal of biological chemistry 2002-09, Vol.277 (36), p.32768-32774
Hauptverfasser:	Mahmud, Taifo, Bode, Helge Bjo¨rn, Silakowski, Barbara, Kroppenstedt, Reiner M., Xu, Mingjie, Nordhoff, Sonja, Ho¨fle, Gerhard, Mu¨ller, Rolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - biosynthesis Bacterial Proteins - genetics Cloning, Molecular Coenzyme A - metabolism DNA - metabolism Fatty Acids - biosynthesis Leucine - metabolism Magnetic Resonance Spectroscopy Methacrylates - metabolism Models, Chemical Stigmatella aurantiaca - metabolism Thiazoles - pharmacology Valerates - metabolism
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