Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma

To elucidate the relationship between genomewide DNA hypomethylation and chromosome instability, 55 prostate carcinoma specimens were analyzed for extent of hypomethylation by Southern blot analysis of LINE‐1 sequence methylation and for loss or gain of chromosomal material by comparative genomic hy...

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Veröffentlicht in:	Genes chromosomes & cancer 2002-09, Vol.35 (1), p.58-65
Hauptverfasser:	Schulz, Wolfgang A., Elo, Jussi P., Florl, Andrea R., Pennanen, Sari, Santourlidis, Simon, Engers, Rainer, Buchardt, Martin, Seifert, Hans-Helge, Visakorpi, Tapio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Chromosome Aberrations Chromosome Deletion Chromosomes, Human, Pair 8 - genetics DNA Methylation Gene Amplification - genetics Humans Long Interspersed Nucleotide Elements - genetics Male Neoplasm Staging Nucleic Acid Hybridization Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism
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