From the Hayflick mosaic to the mosaics of ageing.: Role of stress-induced premature senescence in human ageing

The Hayflick limit—senescence of proliferative cell types—is a fundamental feature of proliferative cells in vitro. Various human proliferative cell types exposed in vitro to many types of subcytotoxic stresses undergo stress-induced premature senescence (SIPS) (also called stress-induced premature...

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