Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey
One hundred sixty-eight volunteers were randomized to receive a placebo or a vitamin C supplement, two tablets daily, over a 60-day period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compare...
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Veröffentlicht in: | Advances in therapy 2002-05, Vol.19 (3), p.151-159 |
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description | One hundred sixty-eight volunteers were randomized to receive a placebo or a vitamin C supplement, two tablets daily, over a 60-day period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compared with the placebo group, the active-treatment group had significantly fewer colds (37 vs 50, P |
doi_str_mv | 10.1007/BF02850271 |
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They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compared with the placebo group, the active-treatment group had significantly fewer colds (37 vs 50, P<.05), fewer days challenged virally (85 vs 178), and a significantly shorter duration of severe symptoms (1.8 vs 3.1 days, P<.03). Consequently, volunteers in the active group were less likely to get a cold and recovered faster if infected. Few side effects occurred with the active treatment, and volunteers reported greatly increased satisfaction with the study supplement compared with any previous form of vitamin C. This well-tolerated vitamin C supplement may prevent the common cold and shorten the duration of symptoms. Volunteers were generally impressed by the protection afforded them during the winter months and the general acceptability of the study medication.</description><identifier>ISSN: 0741-238X</identifier><identifier>EISSN: 1865-8652</identifier><identifier>DOI: 10.1007/BF02850271</identifier><identifier>PMID: 12201356</identifier><language>eng</language><publisher>Edison, NJ: Health Communications</publisher><subject>Ascorbic Acid - therapeutic use ; Biological and medical sciences ; Common Cold - prevention & control ; Dehydroascorbic Acid - therapeutic use ; Diseases of the upper aerodigestive tract ; Double-Blind Method ; Drug Combinations ; Ent and stomatology ; Female ; Health technology assessment ; Humans ; Male ; Medical sciences ; Middle Aged ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Threonine - therapeutic use</subject><ispartof>Advances in therapy, 2002-05, Vol.19 (3), p.151-159</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-93509aa2f57e1bf842f2c944a930642f26c627932409c36908d6c9fd536ad8683</citedby><cites>FETCH-LOGICAL-c344t-93509aa2f57e1bf842f2c944a930642f26c627932409c36908d6c9fd536ad8683</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27928,27929</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13856119$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12201356$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VAN STRATEN, Michael</creatorcontrib><creatorcontrib>JOSLING, Peter</creatorcontrib><title>Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey</title><title>Advances in therapy</title><addtitle>Adv Ther</addtitle><description>One hundred sixty-eight volunteers were randomized to receive a placebo or a vitamin C supplement, two tablets daily, over a 60-day period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compared with the placebo group, the active-treatment group had significantly fewer colds (37 vs 50, P<.05), fewer days challenged virally (85 vs 178), and a significantly shorter duration of severe symptoms (1.8 vs 3.1 days, P<.03). Consequently, volunteers in the active group were less likely to get a cold and recovered faster if infected. Few side effects occurred with the active treatment, and volunteers reported greatly increased satisfaction with the study supplement compared with any previous form of vitamin C. This well-tolerated vitamin C supplement may prevent the common cold and shorten the duration of symptoms. Volunteers were generally impressed by the protection afforded them during the winter months and the general acceptability of the study medication.</description><subject>Ascorbic Acid - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Common Cold - prevention & control</subject><subject>Dehydroascorbic Acid - therapeutic use</subject><subject>Diseases of the upper aerodigestive tract</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Ent and stomatology</subject><subject>Female</subject><subject>Health technology assessment</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Threonine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VAN STRATEN, Michael</creatorcontrib><creatorcontrib>JOSLING, Peter</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Advances in therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VAN STRATEN, Michael</au><au>JOSLING, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey</atitle><jtitle>Advances in therapy</jtitle><addtitle>Adv Ther</addtitle><date>2002-05-01</date><risdate>2002</risdate><volume>19</volume><issue>3</issue><spage>151</spage><epage>159</epage><pages>151-159</pages><issn>0741-238X</issn><eissn>1865-8652</eissn><abstract>One hundred sixty-eight volunteers were randomized to receive a placebo or a vitamin C supplement, two tablets daily, over a 60-day period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compared with the placebo group, the active-treatment group had significantly fewer colds (37 vs 50, P<.05), fewer days challenged virally (85 vs 178), and a significantly shorter duration of severe symptoms (1.8 vs 3.1 days, P<.03). Consequently, volunteers in the active group were less likely to get a cold and recovered faster if infected. Few side effects occurred with the active treatment, and volunteers reported greatly increased satisfaction with the study supplement compared with any previous form of vitamin C. This well-tolerated vitamin C supplement may prevent the common cold and shorten the duration of symptoms. Volunteers were generally impressed by the protection afforded them during the winter months and the general acceptability of the study medication.</abstract><cop>Edison, NJ</cop><pub>Health Communications</pub><pmid>12201356</pmid><doi>10.1007/BF02850271</doi><tpages>9</tpages></addata></record> |
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subjects | Ascorbic Acid - therapeutic use Biological and medical sciences Common Cold - prevention & control Dehydroascorbic Acid - therapeutic use Diseases of the upper aerodigestive tract Double-Blind Method Drug Combinations Ent and stomatology Female Health technology assessment Humans Male Medical sciences Middle Aged Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Threonine - therapeutic use |
title | Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey |
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