Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

Background & Aims: Hepcidin is an antimicrobial peptide thought to be involved in the regulation of intestinal iron absorption. To further investigate its role in this process, we examined hepatic and duodenal gene expression in rats after the switch from a control diet to an iron-deficient diet...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2002-09, Vol.123 (3), p.835-844
Hauptverfasser:	Frazer, David M., Wilkins, Sarah J., Becker, Erika M., Vulpe, Christopher D., Mckie, Andrew T., Trinder, Deborah, Anderson, Gregory J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Cationic Peptides - metabolism Biological and medical sciences Carrier Proteins - metabolism Cation Transport Proteins - metabolism Cytochrome b Group - metabolism Diet Digestive system Duodenum - metabolism Gene Expression - physiology Hepcidins Intestinal Absorption - physiology Investigative techniques, diagnostic techniques (general aspects) Iron - deficiency Iron - metabolism Iron - pharmacokinetics Iron-Binding Proteins Male Medical sciences Oxidoreductases - metabolism Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Rats Rats, Sprague-Dawley
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