Significant Association of Longer Forms of CCTTT Microsatellite Repeat in the Inducible Nitric Oxide Synthase Promoter with Severe Malaria in Thailand

A CCTTT microsatellite repeat in the inducible nitric oxide synthase (iNOS) promoter was analyzed among 256 adult patients with severe Plasmodium falciparum malaria and 179 adult patients with mild malaria living in northwestern Thailand. Genotypes with longer forms of the CCTTT repeat (alleles of ⩾...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 2002-08, Vol.186 (4), p.578-581
Hauptverfasser:	Ohashi, Jun, Naka, Izumi, Patarapotikul, Jintana, Hananantachai, Hathairad, Looareesuwan, Sornchai, Tokunaga, Katsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Animals Biological and medical sciences Blood Cerebral malaria Concise Communication Gene Frequency Genetic Variation Human protozoal diseases Humans Infectious diseases Logistic regression Malaria Malaria, Cerebral - genetics Malaria, Cerebral - parasitology Malaria, Cerebral - physiopathology Malaria, Falciparum - genetics Malaria, Falciparum - parasitology Malaria, Falciparum - physiopathology Medical sciences Microsatellite repeats Microsatellite Repeats - genetics Microsatellites NF-kappa B - genetics Nitric Oxide Synthase - chemistry Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Oxides Parasitic diseases Plasmodium falciparum - pathogenicity Polymerase chain reaction Polymorphism, Genetic Promoter regions Promoter Regions, Genetic - genetics Protozoal diseases Risk Factors Severity of Illness Index Thailand Tropical medicine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!