Identification of a Herpes B Virus–Specific Glycoprotein D Immunodominant Epitope Recognized by Natural and Foreign Hosts

The mapping of linear epitopes of B virus (Cercopithecine herpesvirus 1 and herpes B virus) glycoprotein D (gD) was accomplished by screening the constructed gD epitope library with serum from B virus–infected macaques. The immunodominant epitope, gD (362–370), was identified within the C-terminal r...

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Veröffentlicht in:	The Journal of infectious diseases 2002-08, Vol.186 (4), p.453-461
Hauptverfasser:	Perelygina, Ludmila, Zurkuhlen, Holley, Patrusheva, Irina, Hilliard, Julia K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies Antibodies, Viral - blood Antibody Specificity Antigens, Viral - chemistry Antigens, Viral - genetics Antigens, Viral - immunology Biological and medical sciences Blotting, Western Cercopithecine herpesvirus 1 Enzyme-Linked Immunosorbent Assay Epitope Mapping Epitopes Fundamental and applied biological sciences. Psychology Herpesviridae Infections - diagnosis Herpesviridae Infections - veterinary Herpesviridae Infections - virology Herpesvirus 1, Cercopithecine - immunology Human herpesvirus 1 Human herpesvirus 2 Humans Immunodominant epitopes Immunodominant Epitopes - chemistry Immunodominant Epitopes - genetics Immunodominant Epitopes - immunology Infections Macaca Major Articles Microbiology Molecular Sequence Data Monkey Diseases - diagnosis Monkey Diseases - virology Neutralization Tests Peptides - chemistry Peptides - immunology Proteins Reactivity Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Sequence Analysis, DNA Viral Envelope Proteins - chemistry Viral Envelope Proteins - genetics Viral Envelope Proteins - immunology Virology Viruses
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