Production of interleukin 2 and interleukin 4 by immune CD4−CD8+ and their role in the generation of antigen‐specific cytotoxic T cells

In this report we investigated the production and role of interleukin (IL)2 and IL4 in the generation of antigen‐specific cytotoxic T cells (CTL). We used as our model the ultraviolet‐light‐induced epithelial tumor 1591, a highly immunogenic regressor tumor which evokes a strong cell‐mediated immune...

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Veröffentlicht in:	European journal of immunology 1991-08, Vol.21 (8), p.1863-1871
Hauptverfasser:	Horvat, Branka, Loukides, Jill A., Anandan, Linda, Brewer, Erin, Flood, Patrick M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Antigens - immunology Antigens, Differentiation, T-Lymphocyte - analysis Biological and medical sciences CD4 Antigens - analysis CD8 Antigens Cytotoxicity, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Interleukin-2 - biosynthesis Interleukin-2 - physiology Interleukin-4 - biosynthesis Interleukin-4 - genetics Interleukin-4 - physiology Lymphokines, interleukins ( function, expression) Male Mice Mice, Inbred C3H Neoplasms, Experimental - immunology Regulatory factors and their cellular receptors RNA, Messenger - analysis T-Lymphocytes, Cytotoxic - immunology
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