Increased atrial and brain natriuretic peptides in adults with cyanotic congenital heart disease : Enhanced understanding of the relationship between hypoxia and natriuretic peptide secretion

Brain natriuretic peptide (BNP) levels are used in the evaluation of patients with heart disease, yet there is little understanding of the effect of hypoxia on natriuretic peptide secretion. Furthermore, recent data suggest that oxytocin may mediate stretch-induced atrial natriuretic peptide (ANP) s...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2004-06, Vol.109 (23), p.2872-2877
Hauptverfasser:	HOPKINS, William E, ZENGYI CHEN, FUKAGAWA, Naomi K, HALL, Christian, KNOT, Harm J, LEWINTER, Martin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atrial Appendage - pathology Atrial Natriuretic Factor - blood Atrial Natriuretic Factor - secretion Biological and medical sciences Blood and lymphatic vessels Body Water Cardiology. Vascular system Cell Hypoxia Cells, Cultured - drug effects Cells, Cultured - secretion Cyanosis Cytoplasmic Granules - secretion Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Heart Defects, Congenital - blood Heart Defects, Congenital - physiopathology Humans Hypoxia - blood Hypoxia - etiology Hypoxia - physiopathology Male Medical sciences Myocytes, Cardiac - drug effects Myocytes, Cardiac - secretion Natriuretic Peptide, Brain - blood Natriuretic Peptide, Brain - secretion Neurology Oxygen - pharmacology Oxytocin - blood Oxytocin - pharmacology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Secretory Rate Vascular diseases and vascular malformations of the nervous system
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