Glucose repression in Saccharomyces cerevisiae is directly associated with hexose phosphorylation by hexokinases PI and PII

Genetic and biochemical analyses showed that hexokinase PII is mainly responsible for glucose repression in Saccharomyces cerevisiae, indicating a regulatory domain mediating glucose repression. Hexokinase PI/PII hybrids were constructed to identify the supposed regulatory domain and the repression...

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Veröffentlicht in:	European journal of biochemistry 1991-08, Vol.199 (3), p.511-518
Hauptverfasser:	Rose, M, Albig, W, Entian, K.D
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Glucosidases - metabolism beta-Fructofuranosidase Biological and medical sciences catabolite repression catalytic activity deletions Enzyme Repression fructose Fundamental and applied biological sciences. Psychology genes glucokinase glucose Glucose - pharmacology glycolysis Glycoside Hydrolases - metabolism Growth, nutrition, metabolism, transports, enzymes. Molecular biology hexokinase Hexokinase - biosynthesis Hexokinase - genetics Hexokinase - metabolism hexokinase PI hexokinase PII hexoses Hexoses - metabolism Isoenzymes - biosynthesis Isoenzymes - genetics Isoenzymes - metabolism isomerases isozymes Microbiology molecular biology Mycology phosphoglucoisomerase Phosphorylation promoter regions Saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics
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