Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist

A complete transection of the spinal cord at a low thoracic level induces a paraplegic syndrome that is accompanied by a loss of spinal cord serotonin content. Former experimental data suggest that the central pattern generator for locomotion, located in the lumbar segments of the spinal cord, might...

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Veröffentlicht in:	The European journal of neuroscience 2002-08, Vol.16 (3), p.467-476
Hauptverfasser:	Antri, M., Orsal, D., Barthe, J.-Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Administration Schedule Electromyography EMG Female Hindlimb - innervation Hindlimb - physiology locomotion Locomotion - drug effects Locomotion - physiology locomotor recovery Muscle Contraction - drug effects Muscle Contraction - physiology Muscle, Skeletal - innervation Muscle, Skeletal - physiology Nerve Net - drug effects Nerve Net - metabolism Nerve Net - physiopathology Neurons - drug effects Neurons - metabolism Periodicity quipazine Quipazine - pharmacology Rats Rats, Sprague-Dawley Receptors, Serotonin - drug effects Receptors, Serotonin - metabolism Recovery of Function - drug effects Recovery of Function - physiology serotonin Serotonin Receptor Agonists - pharmacology Spinal Cord - drug effects Spinal Cord - metabolism Spinal Cord - physiopathology Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal Cord Injuries - physiopathology spinal rat Treatment Outcome
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