The Melanocytic Protein Melan‐A/MART‐1 Has a Subcellular Localization Distinct from Typical Melanosomal Proteins

To delineate the role of the melanocyte lineage‐specific protein Melan‐A/MART‐1 in melanogenic functions, a set of biochemical and microscopical studies was performed. Biochemical analysis revealed that Melan‐A/MART‐1 is post‐translationally acylated and undergoes a rapid turnover in a pigmented mel...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2002-09, Vol.3 (9), p.678-693
Hauptverfasser:	De Mazière, Ann M., Muehlethaler, Katja, Van Donselaar, Elly, Salvi, Suzanne, Davoust, Jean, Cerottini, Jean‐Charles, Lévy, Frédéric, Slot, Jan W., Rimoldi, Donata
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm Electrophoresis, Polyacrylamide Gel endosome Golgi Apparatus - metabolism Humans immunoelectron microscopy MART-1 Antigen MART‐1 melanoma melanosome Melanosomes - metabolism Melan‐A Microscopy, Confocal Microscopy, Fluorescence Neoplasm Proteins - metabolism Skin - metabolism Subcellular Fractions - metabolism
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