Effects of pregnancy on insulin receptor in liver, skeletal muscle and adipose tissue of rats

The mechanism responsible for insulin resistance during pregnancy remains unclear. Considerable evidence indicates that the insulin receptor plays an important role in insulin sensitivity. It seems possible that the hormonal milieu during gestation could have an effect on the insulin receptor. In th...

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Veröffentlicht in:	Gynecological endocrinology 2002-06, Vol.16 (3), p.193-205
Hauptverfasser:	GONZALEZ, C. G, ALONSO, A, BALBIN, M, DIAZ, F, FERNANDEZ, S, PATTERSON, A. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Biological and medical sciences Blotting, Northern Blotting, Western Diseases of mother, fetus and pregnancy Estradiol - metabolism Female Gene Expression Regulation Gynecology. Andrology. Obstetrics Insulin - pharmacology Insulin Resistance Liver - drug effects Liver - metabolism Medical sciences Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Phosphorylation Polymerase Chain Reaction Precipitin Tests Pregnancy Pregnancy Complications - metabolism Pregnancy. Fetus. Placenta Progesterone - metabolism Rats Rats, Wistar Receptor, Insulin - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA Probes RNA, Messenger - metabolism Time Factors
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