Impact of donor and recipient cytokine genotypes on renal allograft outcome

Allelic differences in gene promoter or codifying regions have been described to affect regulation of gene expression, consequently increasing or decreasing cytokine production and signal transduction responses to a given stimulus. This observation has been reported for interleukin (IL)-10 (−1082 A/...

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Veröffentlicht in:Transplantation proceedings 2004-05, Vol.36 (4), p.827-829
Hauptverfasser: Ligeiro, D, Sancho, M.R, Papoila, A, Barradinhas, A.M, Almeida, A, Calão, S, Machado, D, Nolasco, F, Guerra, J, Sampaio, M.J, Trindade, H
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