Transplantation of cardiotrophin-1–expressing myoblasts to the left ventricular wall alleviates the transition from compensatory hypertrophy to congestive heart failure in Dahl salt-sensitive hypertensive rats

We investigated whether autologous transplantation of skeletal myoblasts (MB) transferred with cardiotrophin-1 (CT-1) gene could retard the transition to heart failure (HF) in Dahl salt-sensitive (DS) hypertensive rats. Although MB is a therapeutic candidate for chronic HF, little is known about the...

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Veröffentlicht in:Journal of the American College of Cardiology 2004-06, Vol.43 (12), p.2337-2347
Hauptverfasser: Toh, Ryuji, Kawashima, Seinosuke, Kawai, Miki, Sakoda, Tsuyoshi, Ueyama, Tomomi, Satomi-Kobayashi, Seimi, Hirayama, Sonoko, Yokoyama, Mitsuhiro
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Sprache:eng
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