Differential Ca2+ and Sr2+ regulation of intracellular divalent cations release in ventricular myocytes

The regulation of the Ca2+ -induced Ca2+ release (CICR) from intracellular stores is a critical step in the cardiac cycle. The inherent positive feedback of CICR should make it a self-regenerating process. It is accepted that CICR must be governed by some negative control, but its nature is still de...

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Veröffentlicht in:	Cell calcium (Edinburgh) 2004-08, Vol.36 (2), p.119-134
Hauptverfasser:	Zoghbi, M E, Copello, J A, Villalba-Galea, C A, Vélez, P, Diaz Sylvester, P L, Bolaños, P, Marcano, A, Fill, M, Escobar, A L
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Calcium - metabolism Cations, Divalent - metabolism Myocytes, Cardiac - metabolism Rats Sarcoplasmic Reticulum - metabolism Strontium - metabolism Time Factors
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