Management of women with ductal carcinoma in situ of the breast: a population-based study
Background: Increasing incidence of ductal carcinoma in situ (DCIS) confronts patients and clinicians with optimal treatment decisions. This multidisciplinary study investigates therapeutic modalities of DCIS in daily practice and provides recommendations on how to increase quality of care. Patients...
Gespeichert in:
| Veröffentlicht in: | Annals of oncology 2002-08, Vol.13 (8), p.1236-1245 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1245 |
|---|---|
| container_issue | 8 |
| container_start_page | 1236 |
| container_title | Annals of oncology |
| container_volume | 13 |
| creator | Verkooijen, H. M. Fioretta, G. de Wolf, C. Vlastos, G. Kurtz, J. Borisch, B. Schäfer, P. Spiliopoulos, A. Sappino, A. P. Renella, R. Pittet, B. Schmid de Gruneck, J. Wespi, Y. Neyroud-Caspar, I. Bouchardy, C. |
| description | Background: Increasing incidence of ductal carcinoma in situ (DCIS) confronts patients and clinicians with optimal treatment decisions. This multidisciplinary study investigates therapeutic modalities of DCIS in daily practice and provides recommendations on how to increase quality of care. Patients and methods: All women (n = 116) with unilateral DCIS recorded in the Geneva Cancer Registry from 1995 to 1999 were considered. Information concerned patient and tumor characteristics, treatment and outcome. Factors linked to therapy were determined using a case–control approach. Cases were women with treatment of interest and controls other women on the study. Results: Most DCIS cases (62%) were discovered by mammography screening. Ninety (78%) women had breast-conserving surgery (BCS), 18 (16%) mastectomy and seven (6%) bilateral mastectomy. Eight (7%) patients had tumor-positive margins, 18 (16%) lymph node dissection and two (1.7%) chemotherapy. Twenty-five per cent of women with BCS had no radiotherapy, three had radiotherapy after mastectomy. Less than 50% underwent breast reconstruction after mastectomy. Method of discovery, multifocality, tumor localization, size and differentiation were linked to the use of BCS or lymph node dissection. Conclusions: Because of important disparities in DCIS management, recommendations are made to increase quality of care, in particular to prevent axillary dissection or bilateral mastectomy and to increase the use of radiotherapy after BCS. |
| doi_str_mv | 10.1093/annonc/mdf194 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72016107</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72016107</sourcerecordid><originalsourceid>FETCH-LOGICAL-c396t-ccb54e649654e62cbd4f0cf32fa58fdb89b25dc8c1373b5007d2d6ebcf29d3b73</originalsourceid><addsrcrecordid>eNpF0LtvFDEQBnArApFLoEyL3EC3xI_d9ZoOXV6IIJoghTTW-EWc7NqH7VWS_z53uhNXzUjz0zfSh9AJJV8okfwUYkzRnE7WU9keoAXtetkMpKVv0IJIxhvR8fYQHZXyQAjpJZPv0CFldKCsFQv05ydE-OsmFytOHj-l9YafQr3HdjYVRmwgmxDTBDhEXEKdN6zeO6yzg1K_YsCrtJpHqCHFRkNxFpc625f36K2HsbgPu3mMfl-c3yyvmutfl9-X364bw2VfG2N017q-lf1mMKNt64nxnHnoBm_1IDXrrBkM5YLrjhBhme2dNp5Jy7Xgx-jzNneV07_ZlaqmUIwbR4guzUUJRmhPyQY2W2hyKiU7r1Y5TJBfFCVq06Xadqm2Xa79x13wrCdn93pX3hp82gEoBkafIZpQ9o4PXBBG9o9Dqe75_x3yo-oFF526ur1T5MdyeXZ2e6Fu-CuEbo8K</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72016107</pqid></control><display><type>article</type><title>Management of women with ductal carcinoma in situ of the breast: a population-based study</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Verkooijen, H. M. ; Fioretta, G. ; de Wolf, C. ; Vlastos, G. ; Kurtz, J. ; Borisch, B. ; Schäfer, P. ; Spiliopoulos, A. ; Sappino, A. P. ; Renella, R. ; Pittet, B. ; Schmid de Gruneck, J. ; Wespi, Y. ; Neyroud-Caspar, I. ; Bouchardy, C.</creator><creatorcontrib>Verkooijen, H. M. ; Fioretta, G. ; de Wolf, C. ; Vlastos, G. ; Kurtz, J. ; Borisch, B. ; Schäfer, P. ; Spiliopoulos, A. ; Sappino, A. P. ; Renella, R. ; Pittet, B. ; Schmid de Gruneck, J. ; Wespi, Y. ; Neyroud-Caspar, I. ; Bouchardy, C.</creatorcontrib><description>Background: Increasing incidence of ductal carcinoma in situ (DCIS) confronts patients and clinicians with optimal treatment decisions. This multidisciplinary study investigates therapeutic modalities of DCIS in daily practice and provides recommendations on how to increase quality of care. Patients and methods: All women (n = 116) with unilateral DCIS recorded in the Geneva Cancer Registry from 1995 to 1999 were considered. Information concerned patient and tumor characteristics, treatment and outcome. Factors linked to therapy were determined using a case–control approach. Cases were women with treatment of interest and controls other women on the study. Results: Most DCIS cases (62%) were discovered by mammography screening. Ninety (78%) women had breast-conserving surgery (BCS), 18 (16%) mastectomy and seven (6%) bilateral mastectomy. Eight (7%) patients had tumor-positive margins, 18 (16%) lymph node dissection and two (1.7%) chemotherapy. Twenty-five per cent of women with BCS had no radiotherapy, three had radiotherapy after mastectomy. Less than 50% underwent breast reconstruction after mastectomy. Method of discovery, multifocality, tumor localization, size and differentiation were linked to the use of BCS or lymph node dissection. Conclusions: Because of important disparities in DCIS management, recommendations are made to increase quality of care, in particular to prevent axillary dissection or bilateral mastectomy and to increase the use of radiotherapy after BCS.</description><identifier>ISSN: 0923-7534</identifier><identifier>EISSN: 1569-8041</identifier><identifier>DOI: 10.1093/annonc/mdf194</identifier><identifier>PMID: 12181247</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Breast Neoplasms - diagnosis ; Breast Neoplasms - therapy ; breast-conserving therapy ; cancer registry ; Carcinoma, Intraductal, Noninfiltrating - diagnosis ; Carcinoma, Intraductal, Noninfiltrating - therapy ; Case-Control Studies ; Cell Differentiation ; Combined Modality Therapy ; Disease Progression ; ductal carcinoma in situ ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Key words: breast ; lymph node dissection ; Lymph Node Excision ; Mammary gland diseases ; Mammography ; Mastectomy, Segmental ; Medical sciences ; Middle Aged ; Neoplasm Recurrence, Local ; Population Surveillance ; Quality of Life ; Registries ; Risk Factors ; Socioeconomic Factors ; therapy ; Tumors</subject><ispartof>Annals of oncology, 2002-08, Vol.13 (8), p.1236-1245</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-ccb54e649654e62cbd4f0cf32fa58fdb89b25dc8c1373b5007d2d6ebcf29d3b73</citedby><cites>FETCH-LOGICAL-c396t-ccb54e649654e62cbd4f0cf32fa58fdb89b25dc8c1373b5007d2d6ebcf29d3b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13837020$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12181247$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Verkooijen, H. M.</creatorcontrib><creatorcontrib>Fioretta, G.</creatorcontrib><creatorcontrib>de Wolf, C.</creatorcontrib><creatorcontrib>Vlastos, G.</creatorcontrib><creatorcontrib>Kurtz, J.</creatorcontrib><creatorcontrib>Borisch, B.</creatorcontrib><creatorcontrib>Schäfer, P.</creatorcontrib><creatorcontrib>Spiliopoulos, A.</creatorcontrib><creatorcontrib>Sappino, A. P.</creatorcontrib><creatorcontrib>Renella, R.</creatorcontrib><creatorcontrib>Pittet, B.</creatorcontrib><creatorcontrib>Schmid de Gruneck, J.</creatorcontrib><creatorcontrib>Wespi, Y.</creatorcontrib><creatorcontrib>Neyroud-Caspar, I.</creatorcontrib><creatorcontrib>Bouchardy, C.</creatorcontrib><title>Management of women with ductal carcinoma in situ of the breast: a population-based study</title><title>Annals of oncology</title><addtitle>Ann Oncol</addtitle><description>Background: Increasing incidence of ductal carcinoma in situ (DCIS) confronts patients and clinicians with optimal treatment decisions. This multidisciplinary study investigates therapeutic modalities of DCIS in daily practice and provides recommendations on how to increase quality of care. Patients and methods: All women (n = 116) with unilateral DCIS recorded in the Geneva Cancer Registry from 1995 to 1999 were considered. Information concerned patient and tumor characteristics, treatment and outcome. Factors linked to therapy were determined using a case–control approach. Cases were women with treatment of interest and controls other women on the study. Results: Most DCIS cases (62%) were discovered by mammography screening. Ninety (78%) women had breast-conserving surgery (BCS), 18 (16%) mastectomy and seven (6%) bilateral mastectomy. Eight (7%) patients had tumor-positive margins, 18 (16%) lymph node dissection and two (1.7%) chemotherapy. Twenty-five per cent of women with BCS had no radiotherapy, three had radiotherapy after mastectomy. Less than 50% underwent breast reconstruction after mastectomy. Method of discovery, multifocality, tumor localization, size and differentiation were linked to the use of BCS or lymph node dissection. Conclusions: Because of important disparities in DCIS management, recommendations are made to increase quality of care, in particular to prevent axillary dissection or bilateral mastectomy and to increase the use of radiotherapy after BCS.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Breast Neoplasms - diagnosis</subject><subject>Breast Neoplasms - therapy</subject><subject>breast-conserving therapy</subject><subject>cancer registry</subject><subject>Carcinoma, Intraductal, Noninfiltrating - diagnosis</subject><subject>Carcinoma, Intraductal, Noninfiltrating - therapy</subject><subject>Case-Control Studies</subject><subject>Cell Differentiation</subject><subject>Combined Modality Therapy</subject><subject>Disease Progression</subject><subject>ductal carcinoma in situ</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Key words: breast</subject><subject>lymph node dissection</subject><subject>Lymph Node Excision</subject><subject>Mammary gland diseases</subject><subject>Mammography</subject><subject>Mastectomy, Segmental</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Population Surveillance</subject><subject>Quality of Life</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Socioeconomic Factors</subject><subject>therapy</subject><subject>Tumors</subject><issn>0923-7534</issn><issn>1569-8041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0LtvFDEQBnArApFLoEyL3EC3xI_d9ZoOXV6IIJoghTTW-EWc7NqH7VWS_z53uhNXzUjz0zfSh9AJJV8okfwUYkzRnE7WU9keoAXtetkMpKVv0IJIxhvR8fYQHZXyQAjpJZPv0CFldKCsFQv05ydE-OsmFytOHj-l9YafQr3HdjYVRmwgmxDTBDhEXEKdN6zeO6yzg1K_YsCrtJpHqCHFRkNxFpc625f36K2HsbgPu3mMfl-c3yyvmutfl9-X364bw2VfG2N017q-lf1mMKNt64nxnHnoBm_1IDXrrBkM5YLrjhBhme2dNp5Jy7Xgx-jzNneV07_ZlaqmUIwbR4guzUUJRmhPyQY2W2hyKiU7r1Y5TJBfFCVq06Xadqm2Xa79x13wrCdn93pX3hp82gEoBkafIZpQ9o4PXBBG9o9Dqe75_x3yo-oFF526ur1T5MdyeXZ2e6Fu-CuEbo8K</recordid><startdate>20020801</startdate><enddate>20020801</enddate><creator>Verkooijen, H. M.</creator><creator>Fioretta, G.</creator><creator>de Wolf, C.</creator><creator>Vlastos, G.</creator><creator>Kurtz, J.</creator><creator>Borisch, B.</creator><creator>Schäfer, P.</creator><creator>Spiliopoulos, A.</creator><creator>Sappino, A. P.</creator><creator>Renella, R.</creator><creator>Pittet, B.</creator><creator>Schmid de Gruneck, J.</creator><creator>Wespi, Y.</creator><creator>Neyroud-Caspar, I.</creator><creator>Bouchardy, C.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020801</creationdate><title>Management of women with ductal carcinoma in situ of the breast: a population-based study</title><author>Verkooijen, H. M. ; Fioretta, G. ; de Wolf, C. ; Vlastos, G. ; Kurtz, J. ; Borisch, B. ; Schäfer, P. ; Spiliopoulos, A. ; Sappino, A. P. ; Renella, R. ; Pittet, B. ; Schmid de Gruneck, J. ; Wespi, Y. ; Neyroud-Caspar, I. ; Bouchardy, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-ccb54e649654e62cbd4f0cf32fa58fdb89b25dc8c1373b5007d2d6ebcf29d3b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Breast Neoplasms - diagnosis</topic><topic>Breast Neoplasms - therapy</topic><topic>breast-conserving therapy</topic><topic>cancer registry</topic><topic>Carcinoma, Intraductal, Noninfiltrating - diagnosis</topic><topic>Carcinoma, Intraductal, Noninfiltrating - therapy</topic><topic>Case-Control Studies</topic><topic>Cell Differentiation</topic><topic>Combined Modality Therapy</topic><topic>Disease Progression</topic><topic>ductal carcinoma in situ</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Key words: breast</topic><topic>lymph node dissection</topic><topic>Lymph Node Excision</topic><topic>Mammary gland diseases</topic><topic>Mammography</topic><topic>Mastectomy, Segmental</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local</topic><topic>Population Surveillance</topic><topic>Quality of Life</topic><topic>Registries</topic><topic>Risk Factors</topic><topic>Socioeconomic Factors</topic><topic>therapy</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Verkooijen, H. M.</creatorcontrib><creatorcontrib>Fioretta, G.</creatorcontrib><creatorcontrib>de Wolf, C.</creatorcontrib><creatorcontrib>Vlastos, G.</creatorcontrib><creatorcontrib>Kurtz, J.</creatorcontrib><creatorcontrib>Borisch, B.</creatorcontrib><creatorcontrib>Schäfer, P.</creatorcontrib><creatorcontrib>Spiliopoulos, A.</creatorcontrib><creatorcontrib>Sappino, A. P.</creatorcontrib><creatorcontrib>Renella, R.</creatorcontrib><creatorcontrib>Pittet, B.</creatorcontrib><creatorcontrib>Schmid de Gruneck, J.</creatorcontrib><creatorcontrib>Wespi, Y.</creatorcontrib><creatorcontrib>Neyroud-Caspar, I.</creatorcontrib><creatorcontrib>Bouchardy, C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verkooijen, H. M.</au><au>Fioretta, G.</au><au>de Wolf, C.</au><au>Vlastos, G.</au><au>Kurtz, J.</au><au>Borisch, B.</au><au>Schäfer, P.</au><au>Spiliopoulos, A.</au><au>Sappino, A. P.</au><au>Renella, R.</au><au>Pittet, B.</au><au>Schmid de Gruneck, J.</au><au>Wespi, Y.</au><au>Neyroud-Caspar, I.</au><au>Bouchardy, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of women with ductal carcinoma in situ of the breast: a population-based study</atitle><jtitle>Annals of oncology</jtitle><addtitle>Ann Oncol</addtitle><date>2002-08-01</date><risdate>2002</risdate><volume>13</volume><issue>8</issue><spage>1236</spage><epage>1245</epage><pages>1236-1245</pages><issn>0923-7534</issn><eissn>1569-8041</eissn><abstract>Background: Increasing incidence of ductal carcinoma in situ (DCIS) confronts patients and clinicians with optimal treatment decisions. This multidisciplinary study investigates therapeutic modalities of DCIS in daily practice and provides recommendations on how to increase quality of care. Patients and methods: All women (n = 116) with unilateral DCIS recorded in the Geneva Cancer Registry from 1995 to 1999 were considered. Information concerned patient and tumor characteristics, treatment and outcome. Factors linked to therapy were determined using a case–control approach. Cases were women with treatment of interest and controls other women on the study. Results: Most DCIS cases (62%) were discovered by mammography screening. Ninety (78%) women had breast-conserving surgery (BCS), 18 (16%) mastectomy and seven (6%) bilateral mastectomy. Eight (7%) patients had tumor-positive margins, 18 (16%) lymph node dissection and two (1.7%) chemotherapy. Twenty-five per cent of women with BCS had no radiotherapy, three had radiotherapy after mastectomy. Less than 50% underwent breast reconstruction after mastectomy. Method of discovery, multifocality, tumor localization, size and differentiation were linked to the use of BCS or lymph node dissection. Conclusions: Because of important disparities in DCIS management, recommendations are made to increase quality of care, in particular to prevent axillary dissection or bilateral mastectomy and to increase the use of radiotherapy after BCS.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>12181247</pmid><doi>10.1093/annonc/mdf194</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0923-7534 |
| ispartof | Annals of oncology, 2002-08, Vol.13 (8), p.1236-1245 |
| issn | 0923-7534 1569-8041 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72016107 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Breast Neoplasms - diagnosis Breast Neoplasms - therapy breast-conserving therapy cancer registry Carcinoma, Intraductal, Noninfiltrating - diagnosis Carcinoma, Intraductal, Noninfiltrating - therapy Case-Control Studies Cell Differentiation Combined Modality Therapy Disease Progression ductal carcinoma in situ Female Gynecology. Andrology. Obstetrics Humans Key words: breast lymph node dissection Lymph Node Excision Mammary gland diseases Mammography Mastectomy, Segmental Medical sciences Middle Aged Neoplasm Recurrence, Local Population Surveillance Quality of Life Registries Risk Factors Socioeconomic Factors therapy Tumors |
| title | Management of women with ductal carcinoma in situ of the breast: a population-based study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T18%3A21%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Management%20of%20women%20with%20ductal%20carcinoma%20in%20situ%20of%20the%20breast:%20a%20population-based%20study&rft.jtitle=Annals%20of%20oncology&rft.au=Verkooijen,%20H.%20M.&rft.date=2002-08-01&rft.volume=13&rft.issue=8&rft.spage=1236&rft.epage=1245&rft.pages=1236-1245&rft.issn=0923-7534&rft.eissn=1569-8041&rft_id=info:doi/10.1093/annonc/mdf194&rft_dat=%3Cproquest_cross%3E72016107%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72016107&rft_id=info:pmid/12181247&rfr_iscdi=true |