Phadiatop in the diagnosis of respiratory allergy in children: Allergy Project--PROAL
To evaluate the positivity of Phadiatop in children from several Brazilian pediatric allergology centers and to compare its results with the presence of serum specific IgE to inhalant and food allergens. Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmaci...
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| Veröffentlicht in: | Jornal de pediatria 2004-05, Vol.80 (3), p.217-222 |
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| container_title | Jornal de pediatria |
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| creator | Naspitz, Charles K Solé, Dirceu Aguiar, Maria Cecília Chavarria, Maria Letícia Rosário Filho, Nelson Zuliani, Antônio Toledo, Eliana C Barreto, Bruno A P Souza, Leda S F |
| description | To evaluate the positivity of Phadiatop in children from several Brazilian pediatric allergology centers and to compare its results with the presence of serum specific IgE to inhalant and food allergens.
Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmacia) were measured in 457 children from several pediatric allergy centers and in a non-allergic control group (n = 62), distributed across five age groups.
Phadiatop was positive in 305 atopic children (67.6%) and in 25.8% of controls (p < 0.001). Among atopic children the distribution of positive test varied according to age: 7.9% (24/305) among under 2 year-olds, 15.4% (47/305) in 2 to 3 year-olds, 22.0% (67/305) in 3 to 4 year-olds, 19.3% (59/305) in 4 to 5 year-olds and 35.4% (108/305) in 5 to 12 year-olds. No concordance between food allergens and Phadiatop was observed. Analysis of the relationship between positive inhaled allergen RASTs and positive Phadiatop showed best indices with house dust mites (D. pteronyssinus, D. farinae and Blomia tropicalis).
Phadiatop is a useful tool for diagnosing domestic mite allergy. |
| doi_str_mv | 10.2223/1186 |
| format | Article |
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Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmacia) were measured in 457 children from several pediatric allergy centers and in a non-allergic control group (n = 62), distributed across five age groups.
Phadiatop was positive in 305 atopic children (67.6%) and in 25.8% of controls (p < 0.001). Among atopic children the distribution of positive test varied according to age: 7.9% (24/305) among under 2 year-olds, 15.4% (47/305) in 2 to 3 year-olds, 22.0% (67/305) in 3 to 4 year-olds, 19.3% (59/305) in 4 to 5 year-olds and 35.4% (108/305) in 5 to 12 year-olds. No concordance between food allergens and Phadiatop was observed. Analysis of the relationship between positive inhaled allergen RASTs and positive Phadiatop showed best indices with house dust mites (D. pteronyssinus, D. farinae and Blomia tropicalis).
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Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmacia) were measured in 457 children from several pediatric allergy centers and in a non-allergic control group (n = 62), distributed across five age groups.
Phadiatop was positive in 305 atopic children (67.6%) and in 25.8% of controls (p < 0.001). Among atopic children the distribution of positive test varied according to age: 7.9% (24/305) among under 2 year-olds, 15.4% (47/305) in 2 to 3 year-olds, 22.0% (67/305) in 3 to 4 year-olds, 19.3% (59/305) in 4 to 5 year-olds and 35.4% (108/305) in 5 to 12 year-olds. No concordance between food allergens and Phadiatop was observed. Analysis of the relationship between positive inhaled allergen RASTs and positive Phadiatop showed best indices with house dust mites (D. pteronyssinus, D. farinae and Blomia tropicalis).
Phadiatop is a useful tool for diagnosing domestic mite allergy.</description><subject>Age Distribution</subject><subject>Allergens - immunology</subject><subject>Animals</subject><subject>Case-Control Studies</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Demography</subject><subject>Female</subject><subject>Food Hypersensitivity - diagnosis</subject><subject>Food Hypersensitivity - immunology</subject><subject>Humans</subject><subject>Immunoglobulin E - blood</subject><subject>Infant</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Radioallergosorbent Test - methods</subject><subject>Respiratory Hypersensitivity - diagnosis</subject><subject>Respiratory Hypersensitivity - immunology</subject><issn>0021-7557</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFLwzAUx3NQ3Nz8CpKDeKvmpUvSehvDqTDYEHcuafOyZXRNTbrDvr0dK3h6vPf_8efxI2QK7IVznr4CZPKGjBnjkCgh1Ijcx3hgTMhcwh0ZgYCcKynGZLvZa-N051vqGtrtkfbbrvHRReotDRhbF_o4nKmuawy784Wr9q42AZs3Oh-Om-APWHVJsvlez1dTcmt1HfFhmBOyXb7_LD6T1frjazFfJRXvP0wMnxml8krPpMospCWgVjKTiCXDzJZ5makcrbaomQArtDApx0wzmYIyM0wn5Pna2wb_e8LYFUcXK6xr3aA_xUJxBqJv7MGnK1gFH2NAW7TBHXU4F8CKi7LioqzHHoe-U3lE8w8NvtI_YQZndA</recordid><startdate>200405</startdate><enddate>200405</enddate><creator>Naspitz, Charles K</creator><creator>Solé, Dirceu</creator><creator>Aguiar, Maria Cecília</creator><creator>Chavarria, Maria Letícia</creator><creator>Rosário Filho, Nelson</creator><creator>Zuliani, Antônio</creator><creator>Toledo, Eliana C</creator><creator>Barreto, Bruno A P</creator><creator>Souza, Leda S F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200405</creationdate><title>Phadiatop in the diagnosis of respiratory allergy in children: Allergy Project--PROAL</title><author>Naspitz, Charles K ; 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Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmacia) were measured in 457 children from several pediatric allergy centers and in a non-allergic control group (n = 62), distributed across five age groups.
Phadiatop was positive in 305 atopic children (67.6%) and in 25.8% of controls (p < 0.001). Among atopic children the distribution of positive test varied according to age: 7.9% (24/305) among under 2 year-olds, 15.4% (47/305) in 2 to 3 year-olds, 22.0% (67/305) in 3 to 4 year-olds, 19.3% (59/305) in 4 to 5 year-olds and 35.4% (108/305) in 5 to 12 year-olds. No concordance between food allergens and Phadiatop was observed. Analysis of the relationship between positive inhaled allergen RASTs and positive Phadiatop showed best indices with house dust mites (D. pteronyssinus, D. farinae and Blomia tropicalis).
Phadiatop is a useful tool for diagnosing domestic mite allergy.</abstract><cop>Brazil</cop><pmid>15192765</pmid><doi>10.2223/1186</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Age Distribution Allergens - immunology Animals Case-Control Studies Chi-Square Distribution Child Child, Preschool Demography Female Food Hypersensitivity - diagnosis Food Hypersensitivity - immunology Humans Immunoglobulin E - blood Infant Male Mass Screening Radioallergosorbent Test - methods Respiratory Hypersensitivity - diagnosis Respiratory Hypersensitivity - immunology |
| title | Phadiatop in the diagnosis of respiratory allergy in children: Allergy Project--PROAL |
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