Metabolic safety-margins do not differ between cows of high and low genetic merit for milk production
Three galactopoietic stimuli, frequent milking (4X), bovine somatotrophin (bST) and thyroxine (T4) were used in an additive stair-step design to achieve maximum output (metabolic capacity) in six peak-lactation cows of high genetic merit (HT) and six of low genetic merit (LT). A further six of each...
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| Veröffentlicht in: | Journal of dairy research 2004-05, Vol.71 (2), p.141-153 |
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| creator | Knight, Christopher H Alamer, Mohammed A Sorensen, Annette Nevison, Ian M Flint, David J Vernon, Richard G |
| description | Three galactopoietic stimuli, frequent milking (4X), bovine somatotrophin (bST) and thyroxine (T4) were used in an additive stair-step design to achieve maximum output (metabolic capacity) in six peak-lactation cows of high genetic merit (HT) and six of low genetic merit (LT). A further six of each merit were untreated controls (HC, LC). Milk yield was increased significantly by 4X, increased further by the combination of 4X and bST and increased further still and significantly by the full combination of 4X, bST and T4. The magnitude of the yield response to the sequence of treatments did not differ significantly between HT and LT. The yield response to 4X and bST was sustainable without significant loss of body weight or body condition score for the 6 weeks during which these stimuli were administered. The response to the full combination, which included T4, was accompanied by significantly elevated heart rate and significant loss of body weight and condition compared with the combination of 4X and bST. As a result, treatments were discontinued, on an individual cow basis, before completion of this 6-week phase. Time on experiment did not differ between HT and LT. The results do not support the commonly held belief that selective breeding of dairy cows for high milk production has rendered them markedly more susceptible to metabolic disturbances. |
| doi_str_mv | 10.1017/S0022029904000044 |
| format | Article |
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The results do not support the commonly held belief that selective breeding of dairy cows for high milk production has rendered them markedly more susceptible to metabolic disturbances.</description><identifier>ISSN: 0022-0299</identifier><identifier>EISSN: 1469-7629</identifier><identifier>DOI: 10.1017/S0022029904000044</identifier><identifier>PMID: 15190941</identifier><identifier>CODEN: JDRSAN</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Animal husbandry ; Animal productions ; Animals ; Biological and medical sciences ; Body Composition ; body condition ; Body Weight ; Cattle - genetics ; Cattle - physiology ; Dairy cattle ; dairy cows ; energy status ; Female ; Food industries ; Fundamental and applied biological sciences. Psychology ; General aspects ; genetic merit ; Growth Hormone - administration & dosage ; Growth Hormone - adverse effects ; Growth Hormone - blood ; health ; Heart Rate ; Hygiene and safety ; Insulin - blood ; Insulin-Like Growth Factor I - analysis ; lactation ; Lactation - genetics ; Metabolic stress ; Milk production ; milk yield ; milking ; Regression Analysis ; selection methods ; Selective breeding ; somatotropin ; Terrestrial animal productions ; Thyroxine - administration & dosage ; Thyroxine - adverse effects ; Vertebrates</subject><ispartof>Journal of dairy research, 2004-05, Vol.71 (2), p.141-153</ispartof><rights>Proprietors of Journal of Dairy Research 2004</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c460t-76988f1b462a2a73c18320ed1275c6c10d7b0a6a504c63ad5182b9912bfc317b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022029904000044/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27901,27902,55603</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15841169$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15190941$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Knight, Christopher H</creatorcontrib><creatorcontrib>Alamer, Mohammed A</creatorcontrib><creatorcontrib>Sorensen, Annette</creatorcontrib><creatorcontrib>Nevison, Ian M</creatorcontrib><creatorcontrib>Flint, David J</creatorcontrib><creatorcontrib>Vernon, Richard G</creatorcontrib><title>Metabolic safety-margins do not differ between cows of high and low genetic merit for milk production</title><title>Journal of dairy research</title><addtitle>Journal of Dairy Research</addtitle><description>Three galactopoietic stimuli, frequent milking (4X), bovine somatotrophin (bST) and thyroxine (T4) were used in an additive stair-step design to achieve maximum output (metabolic capacity) in six peak-lactation cows of high genetic merit (HT) and six of low genetic merit (LT). 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The results do not support the commonly held belief that selective breeding of dairy cows for high milk production has rendered them markedly more susceptible to metabolic disturbances.</description><subject>Animal husbandry</subject><subject>Animal productions</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Body Composition</subject><subject>body condition</subject><subject>Body Weight</subject><subject>Cattle - genetics</subject><subject>Cattle - physiology</subject><subject>Dairy cattle</subject><subject>dairy cows</subject><subject>energy status</subject><subject>Female</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. 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Academic</collection><jtitle>Journal of dairy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Knight, Christopher H</au><au>Alamer, Mohammed A</au><au>Sorensen, Annette</au><au>Nevison, Ian M</au><au>Flint, David J</au><au>Vernon, Richard G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic safety-margins do not differ between cows of high and low genetic merit for milk production</atitle><jtitle>Journal of dairy research</jtitle><addtitle>Journal of Dairy Research</addtitle><date>2004-05-01</date><risdate>2004</risdate><volume>71</volume><issue>2</issue><spage>141</spage><epage>153</epage><pages>141-153</pages><issn>0022-0299</issn><eissn>1469-7629</eissn><coden>JDRSAN</coden><abstract>Three galactopoietic stimuli, frequent milking (4X), bovine somatotrophin (bST) and thyroxine (T4) were used in an additive stair-step design to achieve maximum output (metabolic capacity) in six peak-lactation cows of high genetic merit (HT) and six of low genetic merit (LT). A further six of each merit were untreated controls (HC, LC). Milk yield was increased significantly by 4X, increased further by the combination of 4X and bST and increased further still and significantly by the full combination of 4X, bST and T4. The magnitude of the yield response to the sequence of treatments did not differ significantly between HT and LT. The yield response to 4X and bST was sustainable without significant loss of body weight or body condition score for the 6 weeks during which these stimuli were administered. The response to the full combination, which included T4, was accompanied by significantly elevated heart rate and significant loss of body weight and condition compared with the combination of 4X and bST. As a result, treatments were discontinued, on an individual cow basis, before completion of this 6-week phase. Time on experiment did not differ between HT and LT. The results do not support the commonly held belief that selective breeding of dairy cows for high milk production has rendered them markedly more susceptible to metabolic disturbances.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>15190941</pmid><doi>10.1017/S0022029904000044</doi><tpages>13</tpages></addata></record> |
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| ispartof | Journal of dairy research, 2004-05, Vol.71 (2), p.141-153 |
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| source | MEDLINE; Cambridge University Press Journals Complete |
| subjects | Animal husbandry Animal productions Animals Biological and medical sciences Body Composition body condition Body Weight Cattle - genetics Cattle - physiology Dairy cattle dairy cows energy status Female Food industries Fundamental and applied biological sciences. Psychology General aspects genetic merit Growth Hormone - administration & dosage Growth Hormone - adverse effects Growth Hormone - blood health Heart Rate Hygiene and safety Insulin - blood Insulin-Like Growth Factor I - analysis lactation Lactation - genetics Metabolic stress Milk production milk yield milking Regression Analysis selection methods Selective breeding somatotropin Terrestrial animal productions Thyroxine - administration & dosage Thyroxine - adverse effects Vertebrates |
| title | Metabolic safety-margins do not differ between cows of high and low genetic merit for milk production |
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