Tyrosine phosphatase 1B and leptin receptor genes and their interaction in type 2 diabetes

. Objectives. The association between three tyrosine phosphatase 1B (PTP1B) gene polymorphisms and type 2 diabetes was examined by comparing the prevalence rates of these polymorphisms in type 2 diabetic patients and healthy control subjects. Furthermore, the association of the polymorphisms and PT...

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Veröffentlicht in:	Journal of internal medicine 2004-07, Vol.256 (1), p.48-55
Hauptverfasser:	Santaniemi, M., Ukkola, O., A. Kesäniemi, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - complications Albuminuria - genetics Biological and medical sciences Body Mass Index Case-Control Studies Cerebrovascular Disorders - complications Coronary Disease - complications Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Gene Frequency General aspects gene–gene interaction Genotype Humans Hypertension - complications Hypertension - genetics leptin receptor Male Medical sciences Middle Aged Peripheral Vascular Diseases - complications Polymerase Chain Reaction - methods Polymorphism, Single Nucleotide Protein Tyrosine Phosphatases - genetics Receptors, Cell Surface - genetics Receptors, Leptin single nucleotide polymorphism type 2 diabetes tyrosine phosphatase 1B
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