Initiation of degenerative joint damage by experimental bleeding combined with loading of the joint: A possible mechanism of hemophilic arthropathy

Objective To investigate the effect of a limited number of experimental joint bleedings, combined with loading of the affected joint, on the development of progressive degenerative joint damage. Methods The right knee of 8 mature beagle dogs was injected with freshly collected autologous blood 3 tim...

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Veröffentlicht in:	Arthritis and rheumatism 2004-06, Vol.50 (6), p.2024-2031
Hauptverfasser:	Hooiveld, Michel J. J., Roosendaal, Goris, Jacobs, Kim M. G., Vianen, Marieke E., van den Berg, H. Marijke, Bijlsma, Johannes W. J., Lafeber, Floris P. J. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chondrocytes - pathology Diseases of the osteoarticular system Dogs Hematologic and hematopoietic diseases Hemophilia A - pathology Hemophilia A - physiopathology Hemorrhage - pathology Joints - pathology Joints - physiopathology Medical sciences Miscellaneous. Osteoarticular involvement in other diseases Platelet diseases and coagulopathies Reproducibility of Results Synovial Membrane - pathology Weight-Bearing
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