Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees

To study determinants of clinical outcome following HCV infection, viral kinetics, immune events, and intrahepatic cytokine markers were compared in 10 naive chimpanzees. Four of the animals cleared HCV; 6 developed persistent infections. All animals developed similar acute infections with increasin...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2004-06, Vol.39 (6), p.1709-1720
Hauptverfasser: Major, Marian E., Dahari, Harel, Mihalik, Kathleen, Puig, Montserrat, Rice, Charles M., Neumann, Avidan U., Feinstone, Stephen M.
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Sprache:eng
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