Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques

Pathological nomograms have allowed urologists to make accurate predictions about the behaviour of localized prostate cancers. However, predicting overall outcome and survival is not solely dependent on tumour characteristics; comorbidity is also a vital determinant of outcome The majority of prosta...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European Urology 2004-07, Vol.46 (1), p.28-41
Hauptverfasser: Singh, Rajinder, O’Brien, T.S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 41
container_issue 1
container_start_page 28
container_title European Urology
container_volume 46
creator Singh, Rajinder
O’Brien, T.S
description Pathological nomograms have allowed urologists to make accurate predictions about the behaviour of localized prostate cancers. However, predicting overall outcome and survival is not solely dependent on tumour characteristics; comorbidity is also a vital determinant of outcome The majority of prostate cancers are diagnosed in men over 65 years of age and many will have significant competing comorbid disease that will need to be accounted when considering eligibility for radical treatment. Most urologists currently make an educated guess about the risk posed by comorbid disease. Such an approach has the potential to allow personal bias to influence what should be an objective measure. This review describes the available methods for objectively assessing comorbid risk and assesses their potential utility to men with localized prostate cancer being considered for radical treatment.
doi_str_mv 10.1016/j.eururo.2004.01.010
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72005194</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0302283804000132</els_id><sourcerecordid>72005194</sourcerecordid><originalsourceid>FETCH-LOGICAL-c358t-22d2af192a693b23e9d924b3dc70c1f7338fab2cac71075a43da9f24870a56233</originalsourceid><addsrcrecordid>eNp9kF1r2zAUhsXoWNJ0_6AUXe3O3pFkxXYvCsF06yCwMdJrIUvHVMG2WsluSX_9FBLYXeGFc_N-cB5CrhnkDNj6-z7HOczB5xygyIElwSeyZFUpslKu4YIsQQDPeCWqBbmMcQ8AQtbiC1kwySohC7kkqvGDD62zbjrQTYwY44DjRN1It97o3r2jpX-Cj5OekDZ6NBhu6Yb-xVeHb9R3tJlDSIk-xV-163XbI92heRrdy4zxinzudB_x6_muyOOP-13zkG1___zVbLaZEbKaMs4t1x2ruV7XouUCa1vzohXWlGBYVwpRdbrlRpuSQSl1IayuO15UJWi55kKsyLdT73Pwx91JDS4a7Hs9op-jKhMlyeoiGYuT0aSnYsBOPQc36HBQDNQRrNqrE1h1BKuAJUGK3Zz753ZA-z90JpkMdycDpi8Tm6CicZhwWRfQTMp69_HCP07yjBc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72005194</pqid></control><display><type>article</type><title>Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Singh, Rajinder ; O’Brien, T.S</creator><creatorcontrib>Singh, Rajinder ; O’Brien, T.S</creatorcontrib><description>Pathological nomograms have allowed urologists to make accurate predictions about the behaviour of localized prostate cancers. However, predicting overall outcome and survival is not solely dependent on tumour characteristics; comorbidity is also a vital determinant of outcome The majority of prostate cancers are diagnosed in men over 65 years of age and many will have significant competing comorbid disease that will need to be accounted when considering eligibility for radical treatment. Most urologists currently make an educated guess about the risk posed by comorbid disease. Such an approach has the potential to allow personal bias to influence what should be an objective measure. This review describes the available methods for objectively assessing comorbid risk and assesses their potential utility to men with localized prostate cancer being considered for radical treatment.</description><identifier>ISSN: 0302-2838</identifier><identifier>EISSN: 1873-7560</identifier><identifier>DOI: 10.1016/j.eururo.2004.01.010</identifier><identifier>PMID: 15183545</identifier><language>eng</language><publisher>Switzerland: Elsevier B.V</publisher><subject>Cardiovascular Diseases - complications ; Cardiovascular Diseases - epidemiology ; Comorbidity ; Comorbidity assessment ; Humans ; Localized prostate cancer ; Male ; Prostatic Neoplasms - complications ; Prostatic Neoplasms - epidemiology ; Risk Assessment ; Validated techniques</subject><ispartof>European Urology, 2004-07, Vol.46 (1), p.28-41</ispartof><rights>2004</rights><rights>Copyright 2004 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c358t-22d2af192a693b23e9d924b3dc70c1f7338fab2cac71075a43da9f24870a56233</citedby><cites>FETCH-LOGICAL-c358t-22d2af192a693b23e9d924b3dc70c1f7338fab2cac71075a43da9f24870a56233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0302283804000132$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>313,314,776,780,788,3537,27899,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15183545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singh, Rajinder</creatorcontrib><creatorcontrib>O’Brien, T.S</creatorcontrib><title>Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques</title><title>European Urology</title><addtitle>Eur Urol</addtitle><description>Pathological nomograms have allowed urologists to make accurate predictions about the behaviour of localized prostate cancers. However, predicting overall outcome and survival is not solely dependent on tumour characteristics; comorbidity is also a vital determinant of outcome The majority of prostate cancers are diagnosed in men over 65 years of age and many will have significant competing comorbid disease that will need to be accounted when considering eligibility for radical treatment. Most urologists currently make an educated guess about the risk posed by comorbid disease. Such an approach has the potential to allow personal bias to influence what should be an objective measure. This review describes the available methods for objectively assessing comorbid risk and assesses their potential utility to men with localized prostate cancer being considered for radical treatment.</description><subject>Cardiovascular Diseases - complications</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Comorbidity</subject><subject>Comorbidity assessment</subject><subject>Humans</subject><subject>Localized prostate cancer</subject><subject>Male</subject><subject>Prostatic Neoplasms - complications</subject><subject>Prostatic Neoplasms - epidemiology</subject><subject>Risk Assessment</subject><subject>Validated techniques</subject><issn>0302-2838</issn><issn>1873-7560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1r2zAUhsXoWNJ0_6AUXe3O3pFkxXYvCsF06yCwMdJrIUvHVMG2WsluSX_9FBLYXeGFc_N-cB5CrhnkDNj6-z7HOczB5xygyIElwSeyZFUpslKu4YIsQQDPeCWqBbmMcQ8AQtbiC1kwySohC7kkqvGDD62zbjrQTYwY44DjRN1It97o3r2jpX-Cj5OekDZ6NBhu6Yb-xVeHb9R3tJlDSIk-xV-163XbI92heRrdy4zxinzudB_x6_muyOOP-13zkG1___zVbLaZEbKaMs4t1x2ruV7XouUCa1vzohXWlGBYVwpRdbrlRpuSQSl1IayuO15UJWi55kKsyLdT73Pwx91JDS4a7Hs9op-jKhMlyeoiGYuT0aSnYsBOPQc36HBQDNQRrNqrE1h1BKuAJUGK3Zz753ZA-z90JpkMdycDpi8Tm6CicZhwWRfQTMp69_HCP07yjBc</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>Singh, Rajinder</creator><creator>O’Brien, T.S</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques</title><author>Singh, Rajinder ; O’Brien, T.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c358t-22d2af192a693b23e9d924b3dc70c1f7338fab2cac71075a43da9f24870a56233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Cardiovascular Diseases - complications</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Comorbidity</topic><topic>Comorbidity assessment</topic><topic>Humans</topic><topic>Localized prostate cancer</topic><topic>Male</topic><topic>Prostatic Neoplasms - complications</topic><topic>Prostatic Neoplasms - epidemiology</topic><topic>Risk Assessment</topic><topic>Validated techniques</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Singh, Rajinder</creatorcontrib><creatorcontrib>O’Brien, T.S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European Urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singh, Rajinder</au><au>O’Brien, T.S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques</atitle><jtitle>European Urology</jtitle><addtitle>Eur Urol</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>46</volume><issue>1</issue><spage>28</spage><epage>41</epage><pages>28-41</pages><issn>0302-2838</issn><eissn>1873-7560</eissn><abstract>Pathological nomograms have allowed urologists to make accurate predictions about the behaviour of localized prostate cancers. However, predicting overall outcome and survival is not solely dependent on tumour characteristics; comorbidity is also a vital determinant of outcome The majority of prostate cancers are diagnosed in men over 65 years of age and many will have significant competing comorbid disease that will need to be accounted when considering eligibility for radical treatment. Most urologists currently make an educated guess about the risk posed by comorbid disease. Such an approach has the potential to allow personal bias to influence what should be an objective measure. This review describes the available methods for objectively assessing comorbid risk and assesses their potential utility to men with localized prostate cancer being considered for radical treatment.</abstract><cop>Switzerland</cop><pub>Elsevier B.V</pub><pmid>15183545</pmid><doi>10.1016/j.eururo.2004.01.010</doi><tpages>14</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0302-2838
ispartof European Urology, 2004-07, Vol.46 (1), p.28-41
issn 0302-2838
1873-7560
language eng
recordid cdi_proquest_miscellaneous_72005194
source MEDLINE; Elsevier ScienceDirect Journals
subjects Cardiovascular Diseases - complications
Cardiovascular Diseases - epidemiology
Comorbidity
Comorbidity assessment
Humans
Localized prostate cancer
Male
Prostatic Neoplasms - complications
Prostatic Neoplasms - epidemiology
Risk Assessment
Validated techniques
title Comorbidity Assessment in Localized Prostate Cancer: A Review of Currently Available Techniques
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T02%3A08%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comorbidity%20Assessment%20in%20Localized%20Prostate%20Cancer:%20A%20Review%20of%20Currently%20Available%20Techniques&rft.jtitle=European%20Urology&rft.au=Singh,%20Rajinder&rft.date=2004-07-01&rft.volume=46&rft.issue=1&rft.spage=28&rft.epage=41&rft.pages=28-41&rft.issn=0302-2838&rft.eissn=1873-7560&rft_id=info:doi/10.1016/j.eururo.2004.01.010&rft_dat=%3Cproquest_cross%3E72005194%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72005194&rft_id=info:pmid/15183545&rft_els_id=S0302283804000132&rfr_iscdi=true