Monocyte activation and T cell inhibition in Plasmodium falciparum-infected placenta

During healthy pregnancy, T helper (Th) 1-type and inflammatory-type responses are down-regulated, and Th2-type and proinflammatory-type responses predominate. In Plasmodium falciparum-infected females, these responses induce enhanced production of tumor necrosis factor- alpha and interferon- gamma....

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Veröffentlicht in:	The Journal of infectious diseases 2004-06, Vol.189 (12), p.2235-2242
Hauptverfasser:	DIOUF, Ibrahima, FIEVET, Nadine, DOUCOURE, Souleymane, NGOM, Mamadou, GAYE, Alioune, DUMONT, Alexandre, CHEIKH TIDIANE NDAO, LE HESRAN, Jean-Yves, CHAOUAT, Gérard, DELORON, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Antigens, CD - metabolism Biological and medical sciences Cells, Cultured Female Flow Cytometry Fundamental and applied biological sciences. Psychology HLA-DR Antigens - metabolism Humans Infectious diseases Lymphocyte Activation Malaria, Falciparum - immunology Malaria, Falciparum - parasitology Malaria, Falciparum - pathology Medical sciences Microbiology Monocytes - immunology Placenta - immunology Placenta - parasitology Placenta - pathology Plasmodium falciparum Plasmodium falciparum - immunology Plasmodium falciparum - pathogenicity Pregnancy Pregnancy Complications, Parasitic - immunology Pregnancy Complications, Parasitic - parasitology Pregnancy Complications, Parasitic - pathology T-Lymphocytes - immunology T-Lymphocytes - pathology Up-Regulation
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