T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene

Vasopressin-activated calcium-mobilizing (VACM-1), a cul-5 gene, is localized on chromosome 11q22-23 close to the gene for Ataxia Telangiectasia in a region associated with a loss of heterozygosity in breast cancer tumor samples. To examine the biological role of VACM-1, we studied the effect of VAC...

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Veröffentlicht in:	Biochemical and biophysical research communications 2004-07, Vol.319 (3), p.817-825
Hauptverfasser:	Burnatowska-Hledin, Maria A, Kossoris, Jennifer B, Van Dort, Christa J, Shearer, Rebecca L, Zhao, Ping, Murrey, Douglas A, Abbott, Jessica L, Kan, Charlene E, Barney, Christopher C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - metabolism Cell Division - physiology Cell growth Cell Line, Tumor Cell Membrane - metabolism Cell Nucleus - metabolism Cullin Proteins - genetics Cullin Proteins - metabolism DNA, Single-Stranded - metabolism Egr-1 Fas Ligand Protein Female Gene Expression Regulation, Neoplastic Humans MAP Kinase Signaling System - physiology MAPK Membrane Glycoproteins - metabolism Mitogen-Activated Protein Kinases - metabolism Mitosis Receptors, Vasopressin - genetics Receptors, Vasopressin - metabolism
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