Subconjunctival antibiotics for acute postcataract extraction endophthalmitis—is it necessary?
To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis. Retrospective cohort study. Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with...
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Veröffentlicht in: | American journal of ophthalmology 2004-06, Vol.137 (6), p.1120-1121 |
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container_title | American journal of ophthalmology |
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creator | Iyer, Mohan N. Han, Dennis P. Yun, Hyun J. Eastwood, Dan Kim, Judy E. Connor, Thomas B. Wirostko, William J. Dev, Sundeep |
description | To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.
Retrospective cohort study.
Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC− group) in the treatment of acute postoperative endophthalmitis.
The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC− group (n = 18) (P = .69), and the mean change in logMAR was –1.36 (improvement) versus –1.34 (P = .93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P = .73).
Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better. |
doi_str_mv | 10.1016/j.ajo.2003.12.042 |
format | Article |
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Retrospective cohort study.
Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC− group) in the treatment of acute postoperative endophthalmitis.
The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC− group (n = 18) (P = .69), and the mean change in logMAR was –1.36 (improvement) versus –1.34 (P = .93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P = .73).
Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.</description><identifier>ISSN: 0002-9394</identifier><identifier>EISSN: 1879-1891</identifier><identifier>DOI: 10.1016/j.ajo.2003.12.042</identifier><identifier>PMID: 15183800</identifier><identifier>CODEN: AJOPAA</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acute Disease ; Aged ; Anti-Bacterial Agents - administration & dosage ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Biological and medical sciences ; Biopsy ; Cataract Extraction ; Chemotherapy, Adjuvant ; Cohort Studies ; Confidence intervals ; Conjunctiva - drug effects ; Endophthalmitis - drug therapy ; Endophthalmitis - microbiology ; Eye ; Eye Infections, Bacterial - drug therapy ; Eye Infections, Bacterial - microbiology ; Humans ; Injections ; Medical sciences ; Patients ; Pharmacology. Drug treatments ; Postoperative Complications - drug therapy ; Postoperative Complications - microbiology ; Retrospective Studies ; Vitreous Body - drug effects</subject><ispartof>American journal of ophthalmology, 2004-06, Vol.137 (6), p.1120-1121</ispartof><rights>2004 Elsevier Inc.</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Elsevier Limited Jun 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c407t-2f2c8586d415d5e24a3791e1c9c8a8de1330144972c42a4b45e84c54dcdc24373</citedby><cites>FETCH-LOGICAL-c407t-2f2c8586d415d5e24a3791e1c9c8a8de1330144972c42a4b45e84c54dcdc24373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ajo.2003.12.042$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15871370$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15183800$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Iyer, Mohan N.</creatorcontrib><creatorcontrib>Han, Dennis P.</creatorcontrib><creatorcontrib>Yun, Hyun J.</creatorcontrib><creatorcontrib>Eastwood, Dan</creatorcontrib><creatorcontrib>Kim, Judy E.</creatorcontrib><creatorcontrib>Connor, Thomas B.</creatorcontrib><creatorcontrib>Wirostko, William J.</creatorcontrib><creatorcontrib>Dev, Sundeep</creatorcontrib><title>Subconjunctival antibiotics for acute postcataract extraction endophthalmitis—is it necessary?</title><title>American journal of ophthalmology</title><addtitle>Am J Ophthalmol</addtitle><description>To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.
Retrospective cohort study.
Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC− group) in the treatment of acute postoperative endophthalmitis.
The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC− group (n = 18) (P = .69), and the mean change in logMAR was –1.36 (improvement) versus –1.34 (P = .93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P = .73).
Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.</description><subject>Acute Disease</subject><subject>Aged</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Cataract Extraction</subject><subject>Chemotherapy, Adjuvant</subject><subject>Cohort Studies</subject><subject>Confidence intervals</subject><subject>Conjunctiva - drug effects</subject><subject>Endophthalmitis - drug therapy</subject><subject>Endophthalmitis - microbiology</subject><subject>Eye</subject><subject>Eye Infections, Bacterial - drug therapy</subject><subject>Eye Infections, Bacterial - microbiology</subject><subject>Humans</subject><subject>Injections</subject><subject>Medical sciences</subject><subject>Patients</subject><subject>Pharmacology. Drug treatments</subject><subject>Postoperative Complications - drug therapy</subject><subject>Postoperative Complications - microbiology</subject><subject>Retrospective Studies</subject><subject>Vitreous Body - drug effects</subject><issn>0002-9394</issn><issn>1879-1891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM-KFDEQh4Mo7uzqA3iRBnFv3aaS9CTBwyKL_2DBg3qOmeoaNk1PZ0zSi958CJ_QJzHDDCgePP0o-Kr41cfYE-AdcFi_GDs_xk5wLjsQHVfiHluB0bYFY-E-W3HORWulVWfsPOexjmut9EN2Bj0YaThfsS8flw3GeVxmLOHOT42fS9iEWALmZhtT43Ep1OxjLuiLTx5LQ9_KIUOcG5qHuL8tt37ahRLyrx8_Q25CaWZCytmn71eP2IOtnzI9PuUF-_zm9afrd-3Nh7fvr1_dtKi4Lq3YCjS9WQ8K-qEnobzUFgjQovFmIJCSg1JWC1TCq43qySjs1YADCiW1vGCXx7v7FL8ulIvbhYw0TX6muGSnwVorZF_BZ_-AY1zSXLs5WCtldN8bWyk4Uphizom2bp_Crj7kgLuDfDe6Kt8d5DsQrsqvO09Pl5fNjoY_GyfbFXh-AnxGP22TnzHkvzijQeoD9_LIURV2Fyi5jIFmpCEkwuKGGP5T4zd0cKNg</recordid><startdate>20040601</startdate><enddate>20040601</enddate><creator>Iyer, Mohan N.</creator><creator>Han, Dennis P.</creator><creator>Yun, Hyun J.</creator><creator>Eastwood, Dan</creator><creator>Kim, Judy E.</creator><creator>Connor, Thomas B.</creator><creator>Wirostko, William J.</creator><creator>Dev, Sundeep</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20040601</creationdate><title>Subconjunctival antibiotics for acute postcataract extraction endophthalmitis—is it necessary?</title><author>Iyer, Mohan N. ; Han, Dennis P. ; Yun, Hyun J. ; Eastwood, Dan ; Kim, Judy E. ; Connor, Thomas B. ; Wirostko, William J. ; Dev, Sundeep</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c407t-2f2c8586d415d5e24a3791e1c9c8a8de1330144972c42a4b45e84c54dcdc24373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Acute Disease</topic><topic>Aged</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Cataract Extraction</topic><topic>Chemotherapy, Adjuvant</topic><topic>Cohort Studies</topic><topic>Confidence intervals</topic><topic>Conjunctiva - drug effects</topic><topic>Endophthalmitis - drug therapy</topic><topic>Endophthalmitis - microbiology</topic><topic>Eye</topic><topic>Eye Infections, Bacterial - drug therapy</topic><topic>Eye Infections, Bacterial - microbiology</topic><topic>Humans</topic><topic>Injections</topic><topic>Medical sciences</topic><topic>Patients</topic><topic>Pharmacology. Drug treatments</topic><topic>Postoperative Complications - drug therapy</topic><topic>Postoperative Complications - microbiology</topic><topic>Retrospective Studies</topic><topic>Vitreous Body - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Iyer, Mohan N.</creatorcontrib><creatorcontrib>Han, Dennis P.</creatorcontrib><creatorcontrib>Yun, Hyun J.</creatorcontrib><creatorcontrib>Eastwood, Dan</creatorcontrib><creatorcontrib>Kim, Judy E.</creatorcontrib><creatorcontrib>Connor, Thomas B.</creatorcontrib><creatorcontrib>Wirostko, William J.</creatorcontrib><creatorcontrib>Dev, Sundeep</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Iyer, Mohan N.</au><au>Han, Dennis P.</au><au>Yun, Hyun J.</au><au>Eastwood, Dan</au><au>Kim, Judy E.</au><au>Connor, Thomas B.</au><au>Wirostko, William J.</au><au>Dev, Sundeep</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Subconjunctival antibiotics for acute postcataract extraction endophthalmitis—is it necessary?</atitle><jtitle>American journal of ophthalmology</jtitle><addtitle>Am J Ophthalmol</addtitle><date>2004-06-01</date><risdate>2004</risdate><volume>137</volume><issue>6</issue><spage>1120</spage><epage>1121</epage><pages>1120-1121</pages><issn>0002-9394</issn><eissn>1879-1891</eissn><coden>AJOPAA</coden><abstract>To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.
Retrospective cohort study.
Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC− group) in the treatment of acute postoperative endophthalmitis.
The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC− group (n = 18) (P = .69), and the mean change in logMAR was –1.36 (improvement) versus –1.34 (P = .93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P = .73).
Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>15183800</pmid><doi>10.1016/j.ajo.2003.12.042</doi><tpages>2</tpages></addata></record> |
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subjects | Acute Disease Aged Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Antibiotics Biological and medical sciences Biopsy Cataract Extraction Chemotherapy, Adjuvant Cohort Studies Confidence intervals Conjunctiva - drug effects Endophthalmitis - drug therapy Endophthalmitis - microbiology Eye Eye Infections, Bacterial - drug therapy Eye Infections, Bacterial - microbiology Humans Injections Medical sciences Patients Pharmacology. Drug treatments Postoperative Complications - drug therapy Postoperative Complications - microbiology Retrospective Studies Vitreous Body - drug effects |
title | Subconjunctival antibiotics for acute postcataract extraction endophthalmitis—is it necessary? |
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