Renal Injury in Apolipoprotein E–Deficient Mice

Hyperlipidemia is thought to accelerate the progression of renal diseases, but the mechanisms by which hyperlipidemia exerts its deleterious effect is still poorly understood. The aim of this study was to describe the renal pathology in a hyperlipidemic mouse strain, the apolipoprotein E–deficient m...

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Veröffentlicht in:	Laboratory investigation 2002-08, Vol.82 (8), p.999-1006
Hauptverfasser:	Wen, Min, Segerer, Stephan, Dantas, Marcio, Brown, Paul A, Hudkins, Kelly L, Goodpaster, Tracy, Kirk, Elizabeth, LeBoeuf, Renée C, Alpers, Charles E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - biosynthesis Apolipoproteins E - deficiency Apolipoproteins E - genetics Biological and medical sciences Disorders of blood lipids. Hyperlipoproteinemia Galectin 3 Hyperlipidemias - physiopathology Immunohistochemistry Kidney - metabolism Kidney - pathology Kidney - physiopathology Kidney Glomerulus - pathology Laboratory Medicine Medical sciences Medicine Medicine & Public Health Metabolic diseases Mice Mice, Knockout Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Pathology Renal failure
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