IL-16 expression in lymphocytes and microglia in HIV-1 encephalitis

IL‐16 is a natural ligand for the CD4 molecule and is known for its chemotactic and anti‐HIV‐1 activities. We determined IL‐16 expression in human brain tissue with HIV‐1 encephalitis by specific immunocytochemistry and showed that infiltrating lymphocytes and activated microglia express IL‐16. IL‐1...

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Veröffentlicht in:	Neuropathology and applied neurobiology 2004-06, Vol.30 (3), p.233-242
Hauptverfasser:	Zhao, M.-L., Si, Q., Lee, S. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Dementia Complex - genetics AIDS Dementia Complex - metabolism astrocyte Astrocytes - metabolism Biological and medical sciences Brain - pathology Cells, Cultured chemokine HIV-1 Human immunodeficiency virus 1 Humans Immunohistochemistry Interleukin-16 - biosynthesis Interleukin-16 - genetics Lipopolysaccharides - pharmacology Lymphocytes - metabolism macrophage Medical sciences Microglia - metabolism microglial nodule Nef Neurology Paraffin Embedding Stimulation, Chemical T-Lymphocytes - metabolism Tissue Fixation
Online-Zugang:	Volltext
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