Evolutionary rate heterogeneity in proteins with long disordered regions

The dominant view in protein science is that a three-dimensional (3-D) structure is a prerequisite for protein function. In contrast to this dominant view, there are many counterexample proteins that fail to fold into a 3-D structure, or that have local regions that fail to fold, and yet carry out f...

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Veröffentlicht in:	Journal of molecular evolution 2002-07, Vol.55 (1), p.104-110
Hauptverfasser:	Brown, Celeste J, Takayama, Sachiko, Campen, Andrew M, Vise, Pam, Marshall, Thomas W, Oldfield, Christopher J, Williams, Christopher J, Dunker, A Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Databases, Protein Deoxyribonucleic acid DNA Evolution, Molecular Evolutionary biology Genomics Heterogeneity Models, Genetic Molecular biology Proteins Proteins - genetics PubMed Viral Proteins - chemistry Viral Proteins - genetics
Online-Zugang:	Volltext
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