Evaluating machine learning approaches for aiding probe selection for gene-expression arrays

Microarrays are a fast and cost-effective method of performing thousands of DNA hybridization experiments simultaneously. DNA probes are typically used to measure the expression level of specific genes. Because probes greatly vary in the quality of their hybridizations, choosing good probes is a dif...

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Veröffentlicht in:	Bioinformatics 2002-07, Vol.18 Suppl 1 (1), p.S164-S171
Hauptverfasser:	Tobler, J B, Molla, M N, Nuwaysir, E F, Green, R D, Shavlik, J W
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Artificial Intelligence Bayes Theorem DNA Probes Gene Expression Profiling - methods Models, Genetic Models, Statistical Neural Networks (Computer) Oligonucleotide Array Sequence Analysis - methods Reproducibility of Results Sensitivity and Specificity Sequence Analysis, DNA
Online-Zugang:	Volltext
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