Whole-Body Hypothermia for Neonatal Encephalopathy: Animal Observations as a Basis for a Randomized, Controlled Pilot Study in Term Infants

Modest reduction in brain temperature is a promising therapy to reduce brain damage after neonatal encephalopathy as a result of acute perinatal asphyxia. The efficacy of modest hypothermia may in part be dependent on the stability of the desired brain temperature. The objective of this study was 1)...

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Veröffentlicht in:	Pediatrics (Evanston) 2002-08, Vol.110 (2), p.377-385
Hauptverfasser:	Shankaran, Seetha, Laptook, Abbot, Wright, Linda L, Ehrenkranz, Richard A, Donovan, Edward F, Fanaroff, Avroy A, Stark, Ann R, Tyson, Jon E, Poole, Kenneth, Carlo, Waldemar A, Lemons, James A, Oh, William, Stoll, Barbara J, Papile, Lu-Ann, Bauer, Charles R, Stevenson, David K, Korones, Sheldon B, McDonald, Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Asphyxia Neonatorum - complications Babies Biological and medical sciences Brain damage Brain Diseases - etiology Brain Diseases - prevention & control Care and treatment Clinical trials Diseases of mother, fetus and pregnancy Encephalopathy Feasibility Studies Gynecology. Andrology. Obstetrics Health aspects Humans Hypothermia Hypothermia, Induced Hypothermia, Induced - methods Induced hypothermia Infant, Newborn Medical sciences Models, Animal Pediatrics Pilot Projects Pregnancy. Fetus. Placenta Prevention Swine Therapy
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