Biologically active steroidal glycosides from Tribulus terrestris

The steroidal saponin constituents obtained from Tribulus terrestris were tested for their antimicrobial and cytotoxic effects. The spirostanol-based steroidal saponins 1-3 exhibited remarkable activity against fungal organisms (Candida albicans and Cryptococcus neoformans) and cancer cell lines [hu...

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Veröffentlicht in:	Pharmazie 2002-07, Vol.57 (7), p.491-493
Hauptverfasser:	BEDIR, E, KHAN, I. A, WALKER, L. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Bacteria - drug effects Biological and medical sciences Drug Screening Assays, Antitumor Fungi - drug effects General pharmacology Glycosides - isolation & purification Glycosides - pharmacology Humans Medical sciences Microbial Sensitivity Tests Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plants, Medicinal - chemistry Steroids - isolation & purification Steroids - pharmacology Tumor Cells, Cultured Zygophyllaceae - chemistry Zygophyllaceae - metabolism
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