Effects of bilateral uterine vessel ligation on skeletal growth in rats
The aim of the present study was to assess the catch-up growth in the postcranial skeleton of intrauterine growth retarded (IUGR) rats. Male and female Wistar rats were assigned to one of the following groups: controls, sham-operated, IUGR. The IUGR was produced by uterine vessels bending (day 14th...
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| Veröffentlicht in: | Clinical and experimental obstetrics & gynecology 2002, Vol.29 (2), p.121-125 |
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| container_title | Clinical and experimental obstetrics & gynecology |
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| creator | Oyhenart, E E Guimarey, L M Fucini, M C Quintero, F A Orden, B |
| description | The aim of the present study was to assess the catch-up growth in the postcranial skeleton of intrauterine growth retarded (IUGR) rats. Male and female Wistar rats were assigned to one of the following groups: controls, sham-operated, IUGR. The IUGR was produced by uterine vessels bending (day 14th of pregnancy). Trunk, pelvis, femur and humerus were measured on Rx of each animal, from I to 84 days of age. Data were processed by repeated analysis of variance and LSD post hoc test. The reduced placental blood flow disturbed the skeletal growth in pups, with the axial skeleton relatively more affected than the bones of the extremities. The catch up only took place in femur length of both sexes. The widths of long bones remained significantly retarded. We concluded that nutritional rehabilitation during the postnatal period might not be enough to allow a complete growth recovery. |
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| ispartof | Clinical and experimental obstetrics & gynecology, 2002, Vol.29 (2), p.121-125 |
| issn | 0390-6663 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Animals, Newborn Bone Development - physiology Female Femur - growth & development Fetal Growth Retardation - physiopathology Male Rats Rats, Wistar Sperm Injections, Intracytoplasmic |
| title | Effects of bilateral uterine vessel ligation on skeletal growth in rats |
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