Do Long-Chain Acyl-CoA Synthetases Regulate Fatty Acid Entry into Synthetic Versus Degradative Pathways?

Recent studies suggest that the long-chain acyl-CoA synthetases (ACS) may play a role in channeling fatty acids either toward complex lipid synthesis and storage or toward oxidation. Each of the five members of the ACS family that has been cloned has a distinct tissue distribution and subcellular lo...

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Veröffentlicht in:	The Journal of nutrition 2002-08, Vol.132 (8), p.2123-2126
Hauptverfasser:	Coleman, Rosalind A., Lewin, Tal M., Van Horn, Cynthia G., Gonzalez-Baró, Maria R.
Format:	Artikel
Sprache:	eng
Schlagworte:	acyl coenzyme A Animals binding proteins Biological and medical sciences Coenzyme A Ligases - metabolism corticotropin diabetes Fatty acids Fatty Acids, Nonesterified - biosynthesis Fatty Acids, Nonesterified - metabolism Fundamental and applied biological sciences. Psychology Homeostasis Humans Isoenzymes - metabolism Lipids. Glycolipids liver long-chain-fatty-acid-CoA ligase Metabolisms and neurohumoral controls Nutritional Physiological Phenomena oxidation peroxisomes Substrate Specificity tissue distribution transcription factors triacylglycerol triacylglycerols Vertebrates: anatomy and physiology, studies on body, several organs or systems
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