Immunomodulatory effects of glatiramer acetate on superantigen- and mitogen-induced T-cell stimulation in vitro

Glatiramer acetate (GA) interferes with antigen recognition and modulates cytokine secretion of T cells in an antigen-specific manner. Here we analysed the capacity of GA to modulate proliferative responses and cytokine secretion of peripheral blood mononuclear cells (PBMCs) in response to antigen-i...

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Veröffentlicht in:	Multiple sclerosis 2002-08, Vol.8 (4), p.307-309
Hauptverfasser:	Schmidt, S, Balzer, S, Nüllen, C, Schmidt, M, Pohl, C, von Rücker, A, Klockgether, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cell Division - drug effects Enterotoxins - pharmacology Female Glatiramer Acetate Humans Immunomodulators Immunosuppressive Agents - pharmacology In Vitro Techniques Interferon-gamma - secretion Interleukin-4 - secretion Lymphocyte Activation - drug effects Male Medical sciences Mitogens - pharmacology Multiple Sclerosis - drug therapy Multiple Sclerosis - immunology Peptides - pharmacology Pharmacology. Drug treatments Phytohemagglutinins - pharmacology Superantigens - pharmacology T-Lymphocytes - cytology T-Lymphocytes - drug effects T-Lymphocytes - secretion Tumor Necrosis Factor-alpha - secretion
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