The role of descending fibers from the rostral ventromedial medulla in opioid analgesia in rats

There has been controversy as to whether the contribution of descending fibers from the rostral ventromedial medulla to opioid analgesia depends on the nature of the noxious stimulus eliciting pain. In the present study, inactivation of descending fibers by microinjection of muscimol (50 ng) in the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 2002-08, Vol.449 (1-2), p.75-84
Hauptverfasser:	Gilbert, Annie-Kim, Franklin, Keith B.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Analgesics, Opioid - pharmacology Animals Behavior, Animal - drug effects Biological and medical sciences Buprenorphine Buprenorphine - pharmacology Dose-Response Relationship, Drug Efferent Pathways - cytology Efferent Pathways - drug effects Formaldehyde Formalin test GABA Agonists - administration & dosage GABA Agonists - pharmacology Hot plate Hot Temperature - adverse effects Immersion - adverse effects Injections, Intraventricular Male Medical sciences Medulla Oblongata - cytology Medulla Oblongata - drug effects Medulla Oblongata - physiology Microinjections Morphine Muscimol - administration & dosage Muscimol - pharmacology Nerve Fibers - drug effects Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Nociception Pain Measurement - drug effects Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems Pharmacology. Drug treatments Rats Rats, Wistar Reaction Time - drug effects Tail immersion
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!