Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons

Alternative medicines such as herbal products are increasingly being used for preventive and therapeutic purposes. Ginseng is the best known and most popular herbal medicine used worldwide. In spite of some beneficial effects of ginseng on the CNS, little scientific evidence shows at the cellular le...

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Veröffentlicht in:	Biochemical and biophysical research communications 2002-08, Vol.296 (2), p.247-254
Hauptverfasser:	Kim, Sunoh, Ahn, Kwangseog, Oh, Tae Hwan, Nah, Seung-Yeol, Rhim, Hyewhon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Calcium Signaling - physiology Cells, Cultured Central Nervous System Agents - pharmacology Excitatory Amino Acid Agonists - metabolism Excitotoxicity Fluorescent Dyes - metabolism Fura-2 Fura-2 - metabolism Ginseng Ginsenosides Glutamic Acid - metabolism Herbal Medicine Hippocampal neurons Hippocampus - cytology Hippocampus - metabolism Intracellular Ca 2 N-Methylaspartate - metabolism Neurons - cytology Neurons - drug effects Neurons - metabolism NMDA Panax - chemistry Patch-Clamp Techniques Patch–clamp Plants, Medicinal Rats Rats, Sprague-Dawley Receptors, N-Methyl-D-Aspartate - metabolism Saponins - pharmacology
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