Sequential changes in redox status and nitric oxide synthases expression in the liver after bile duct ligation

Bile duct ligation (BDL) in rats induces portal fibrosis. This process has been linked to changes in the oxidative state of the hepatic cells and in the production of nitric oxide. Our objective was to find possible temporal connections between hepatic redox state, NO synthesis and liver injury. In...

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Veröffentlicht in:	Life sciences (1973) 2004-06, Vol.75 (6), p.717-732
Hauptverfasser:	Vázquez-Gil, M.José, Mesonero, M.José, Flores, Olga, Criado, Manuela, Hidalgo, Froilán, Arévalo, Miguel A, Sánchez-Rodrı́guez, Angel, Tuñón, M.Jesús, López-Novoa, José M, Esteller, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile duct ligation Bile Ducts, Extrahepatic - surgery Blood Pressure - physiology Blotting, Western Disease Models, Animal Fibrosis Hydroxyproline - analysis Hydroxyproline - metabolism Immunoenzyme Techniques Lipid Peroxidation - physiology Liver Liver - chemistry Liver - enzymology Liver Cirrhosis, Experimental - enzymology Liver Cirrhosis, Experimental - etiology Liver Cirrhosis, Experimental - pathology Male Nitrates - metabolism Nitric oxide Nitric oxide synthase Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Nitrites - metabolism Oxidative Stress Rats Rats, Wistar
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