Plasticity and reprogramming of differentiated cells in amphibian regeneration

Key Points Regenerative ability is widespread in metazoan phylogeny, but has been lost in many species for reasons that are not understood. The champions of regeneration among adult verterbrates are the urodele amphibians, such as the newt, which can regenerate their limbs, jaws, lens and large sect...

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Veröffentlicht in:	Nature reviews. Molecular cell biology 2002-08, Vol.3 (8), p.566-574
Hauptverfasser:	Brockes, Jeremy P., Kumar, Anoop
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphibians Animals Biochemistry Biology Biomedical and Life Sciences Cancer Research Cardiomyocytes Cartilage Cell Biology Cell cycle Cell Cycle - physiology Cell Differentiation - physiology Cell division Comparative studies Developmental Biology Extremities - physiology Heart Heart - physiology Iris - physiology Life Sciences Mammals Muscles - anatomy & histology Muscles - physiology Phylogenetics Phylogeny Plasticity Purines - metabolism Regeneration - physiology Reptiles & amphibians review-article Stem Cells Urodela Urodela - embryology Urodela - physiology
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