Dry eye: diagnosis and current treatment strategies

One in four patients attending ophthalmic clinics report symptoms of dry eye, making it one of the most common complaints seen by ophthalmologists. Aqueous-layer deficiency is the most common form of dry eye and is frequently caused by decreased secretion of tears by the lacrimal glands. Evaporative...

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Veröffentlicht in:Current allergy and asthma reports 2004-07, Vol.4 (4), p.314-319
Hauptverfasser: O'Brien, Paul D, Collum, Louis M T
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description One in four patients attending ophthalmic clinics report symptoms of dry eye, making it one of the most common complaints seen by ophthalmologists. Aqueous-layer deficiency is the most common form of dry eye and is frequently caused by decreased secretion of tears by the lacrimal glands. Evaporative dry eye is often secondary to meibomian gland disease and results in a defective lipid layer. Tear replacement or preservation using artificial tears and/or punctal occlusion are the mainstay of treatment. Newer forms of therapy were designed to modify the underlying disease process. These include the use of topical cyclosporin A, autologous serum, and sodium hyaluronate drops, which suppress underlying inflammation, provide growth factors, and prevent the onset of squamous metaplasia in ocular surface epithelium. Hormonal therapy might have a role in the future of dry eye therapy.
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subjects Androgens - biosynthesis
Androgens - therapeutic use
Anti-Inflammatory Agents - therapeutic use
Cyclosporine - therapeutic use
Dry Eye Syndromes - diagnosis
Dry Eye Syndromes - physiopathology
Dry Eye Syndromes - therapy
Humans
Hyaluronic Acid - therapeutic use
Lacrimal Apparatus - physiopathology
Medical treatment
Ophthalmic Solutions - therapeutic use
Tears - metabolism
title Dry eye: diagnosis and current treatment strategies
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