Effect of Iloprost ® on endothelin-1-induced free radical activation in rabbit brain stem

Iloprost, a stable analogue of prostacyclin, was used to reverse the early period of vasoconstriction provoked by Endothelin-1 by administering into the rabbit basilar artery. We observed if this produced an effect on the central nervous system parenchyma mediated by free radical system. The red neu...

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Veröffentlicht in:	Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2004-07, Vol.71 (1), p.7-11
Hauptverfasser:	Keskil, İ.Semih, Kemali Baykaner, M., Aricioğlu, Aysel, Kaymaz, Memduh, Uysal, Selçuk, Ataoğlu, Ömür, Balabanli, Barbaros, Ercan, Sevim, Çeviker, Necdet
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basilar Artery Biological and medical sciences Brain Chemistry Brain Stem - metabolism Endothelin-1 - administration & dosage Free Radicals - metabolism Fundamental and applied biological sciences. Psychology Iloprost - administration & dosage Injections, Intra-Arterial Malondialdehyde - analysis Neurons - metabolism Rabbits Superoxide Dismutase - analysis Vasoconstriction - drug effects Vasodilator Agents - administration & dosage Vertebrates: endocrinology
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